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… algae and plants. These molecules, which are not essential for fundamental growth, provide critical advantages to the … and their roles in the environment, can unlock new avenues for bio-based products and bioenergy crop enhancement. The … support users, our efforts include developing computational tools for predicting biosynthetic gene clusters (BGCs), …

… Every approved proposal starts with a User Agreement — before any work can begin, including the submission of samples for sequencing, or the submission of sequencing data for … rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is …

… Mexico, and an incredibly bright guy who’s been thinking for a long time about the evolution and natural products … feature of many metabolites being produced throughout the whole pathway. And that is what we call secondary … I have the feeling that once we have the synthetic biology tools, we finally are in a position to exploit secondary …

… An assay used for profiling transcription factor binding sites across entire genomes. This technology has been further scaled to a … samples in 96-well plates on automated liquid handler platforms, substantially increasing efficiency and scalability. … genomes of uncultivated microbes. We also apply labeling strategies that allow us to select specific uncultivated …

… I wanted to tell you about in this introduction. First and foremost, our interview this week is with Professor Brian … And it was a big deal. And you really had– I mean, the whole sequencing endeavor, had a cost, how much blood, … an undergraduate and not succeeding and still using all the tools from mechanistic enzymology to natural product …

… The Joint Genome Institute and the Molecular Foundry have launched a … proposal call . This represents a unique opportunity for researchers to request the capabilities and expertise of … science, accelerating discoveries and developing transformative bio-based technologies that address challenges in …

… The CSP Functional Genomics call is to enable users to perform state-of-the-art functional genomics research and to help them translate genomic information into biological function.  The emphasis is on … ‘omics capabilities to enhance understanding of gene and genome function, particularly those not readily achievable …

… material of uncultivated taxa of interest. One such effort is targeted at environmental cells that are from … genomes are critical to serve as phylogenetic anchors for metagenomes studies.  While uncovering the metabolic … or phenotype of interest, prior to and in conjunction with whole genome sequencing. …

… Minerals and Materials call represents a unique opportunity for researchers to request the capabilities and expertise of both the Joint Genome Institute and the Molecular Foundry in one research … provides customized analysis, the JGI also participates in publication of results. Go here for additionial information, …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … it’s a little hard to find in print, but we live in the information age and the ebook version is available at most … finding new sources is somewhat problematic. And there’s a whole process to this, that can be really time consuming …

… by microbial partners. We use a variety of genomics-powered tools to study this complexity, including single-cell and … experimental characterization methods, in addition to bioinformatics tools to elucidate phage function in this tripartite … Selected Publications …

… Doering and Bryce Foster and too many others to name at JGI for the last two years or so. SMC is now released and ready … of always working on natural products but just different tools and how to really access and manipulate these pathways … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever …