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… on this: Most of the machinery in any living organism are proteins, which are made up of chains of amino acids. … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the … of fantastic science, mainly in marine natural products structure elucidation, and he trained some of the greats in …
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… “tail of the acyl homoserine lactone” can have different structures, and that is akin to what you’re referring to … more structural diversity — so that one uses acyl carrier proteins as co-substrate. So the other ones they use CoA … up on previous Natural Prodcast episodes here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …
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… study on ethnobotany of some of the plants that people were using for medicines in this very remote village. And so it … And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … easy to search for because there are patterns of domains, protein domains that you look for. And if you find those all …
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… that you need to do these coordination bonds, then many structures will be able to work. So, for example, in that … be the amino acid that is relevant for the synthesis of proteins, and will more often end up in the active site of … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …
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Our data platforms are a key resource for the broader scientific … … Download plant, algal, fungal and microbial genomes and metagenomes — top-quality genomic data, open to all … of microbial communities based on their metagenome sequence, in the context of reference isolate genomes …
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… sends Project Manager (PM) a list of organism names (or for metagenomes, sample names). Need help naming your … metadata to JGI database for shipping approval (n/a if using web-based form) All shipments originating outside the … pipelines. You will receive automated emails as raw sequence data becomes available, and as analysis is …
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… of Science through high performance computing (HPC) and data analysis. The DOE Systems Biology Knowledgebase ( … … For sequencing projects, once work is under way, raw sequence data is released to NCBI’s Sequence Read Archive on … more customized analysis, the JGI also participates in publication of results. … Submission … More on Sequencing …
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… of samples for sequencing, or the submission of sequencing data for synthesis. This agreement, required by the DOE for … others: indemnification, patent rights, rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is …
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There is no cost to the user and no granting of funds. All data is made publicly available in accordance with JGI’s Data Policy . In cases where the JGI provides customized analysis, the JGI also participates in publication of results. … All proposals undergo technical …
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Research in the Eloe-Fadrosh group focuses on using genome-resolved metagenomic approaches to identify and … computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial … Microbiology , 15032. 10.1038/nmicrobiol.2015.32 … Selected Publications … For further details, please reach out to the …
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… and I talked about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, … cluster database, and a tool for predicting natural product structures from genomes. And I was writing grants furiously … with sequence similarity, either we just looked at which protein domains are in a gene cluster or we did sequence …
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