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… has got to be new, or at least we hope. This is what we’re using to get funding, but. DAN UDWARY: Well, you’ve seen … Everything that we’re finding seems to be a new structure, and the microorganisms are novel. I mean, we have … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever …

… also tackles challenges posed by environmental change, focusing on plant resilience — highlighting the vulnerabilities … understanding of plant diversity and integrating various data types to explore the molecular mechanisms behind … including deep learning algorithms for gene annotation and protein folding models, to improve the accuracy of …

… on this: Most of the machinery in any living organism are proteins, which are made up of chains of amino acids. … The other way – the RiPP way, is to make a protein using the normal cellular way of making proteins, with a … the end, we took an approach that was kind of a simplified metagenome sequencing approach to pick this system apart.  …

… the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our group also … access to cutting-edge cell sorting, DNA amplification, and sequence analysis to recover the genomes of uncultivated … now uses laser microdissection to selectively isolate and sequence microbial aggregates after first imaging with …

… I could see myself going in the future. So, then we were using these probes to look at host pathogen interactions … “tail of the acyl homoserine lactone” can have different structures, and that is akin to what you’re referring to … more structural diversity — so that one uses acyl carrier proteins as co-substrate. So the other ones they use CoA …

… study on ethnobotany of some of the plants that people were using for medicines in this very remote village. And so it … And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … easy to search for because there are patterns of domains, protein domains that you look for. And if you find those all …

… 1) Complete Sample Metadata form Sample metadata is collected via spreadsheet or entered into a web … sends Project Manager (PM) a list of organism names (or for metagenomes, sample names).  Need help naming your … pipelines.  You will receive automated emails as raw sequence data becomes available, and as analysis is …

… of samples for sequencing, or the submission of sequencing data for synthesis. This agreement, required by the DOE for … others: indemnification, patent rights, rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is …

… you here. Tell me what you think the terms we should be using for what we do are, and why there and why it’s … that you need to do these coordination bonds, then many structures will be able to work. So, for example, in that … be the amino acid that is relevant for the synthesis of proteins, and will more often end up in the active site of …

… of Science through high performance computing (HPC) and data analysis.  The DOE Systems Biology Knowledgebase ( KBase ) integrates systems biology data and tools to help predict biological function.   To … NERSC and KBase issued a call for proposals in biological data science as part of the FICUS initiative. Proposals …

… and I talked about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, … cluster database, and a tool for predicting natural product structures from genomes. And I was writing grants furiously … with sequence similarity, either we just looked at which protein domains are in a gene cluster or we did sequence …