Search

… you understand what’s happened so far in the conversation between me and Alison. In the previous episodes we talked … we’re going to finish up by talking about the modern, post-golden age history of natural products discovery, and we’ll … problematic. And there’s a whole process to this, that can be really time consuming because you need to, you know, …

… you guys. Schedules are hard. But, I’m working on it because I really do want you all to hear this great … to understand the enzymology of their synthases so that we can start to use the DNA sequence to predict or just … the language of microbial cell-cell communication. And he told us about his work in inverse stable isotopic labeling, …

… on the Tiny Earth project, which you’ll hear him describe. [ Go here to learn more about Tiny Earth and the JGI’s … trying to sequence is, you have to have a sequencer that can read longer than the repeat, otherwise, you have no idea … agencies and the popular news recently because a lot of soldiers in the Iraq and Afghanistan area were coming back …

… us who work in fungal natural products, especially in the old days, saw how hard it was – it felt kind of like … work in simpler systems, like bacteria, where we figure we can make more progress faster, which is sometimes true. … stick them together to make small peptides. Those are fun, because the host organism can use whatever amino acids it …

… link to it in the show notes. Which I’ll remind you, you can always find at naturalprodcast.com . You should know … the texture is kind of like– Dan, do they look like a mold, like a fungi or so? DAN UDWARY: Not really. They’re … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all …

… welcome to the first episode of Natural Prodcast. First, maybe, a little bit of background. My name is Dan Udwary. I – … podcast about natural products. And natural products is an older term for the special, natural chemical compounds that … about what they need to advance their science, and what JGI can do to help that. So here we are. This is the first …

… from Simon Fraser University in British Columbia, Canada. This is the last of the podcasts we recorded in my … Institution of Oceanography. Roger was splitting his time between Bill Gerwick’s lab and doing research in Panama … the algorithm had done was actually accurate. And so we told people that if they would curate 1000 entries, that that …

… and other bioenergy solutions.  The program has been a pioneering effort in functional genomics since 2012, … genomics, focusing on developing genetic systems that can address global energy and environmental challenges. The … These advancements contribute to the development of new biofuels and sustainable biochemicals. The DNA Synthesis …

… of questions from scientists about whether and how they can work with the JGI, and, you know, I’m always really … what kinds of research to support and conduct. I already told you what a CSP is, but one other program I think we … do the bioinformatics and to synthesize these results into publication? So there’s this really important because we …

… Hey, Dan. Dan Udwary: Today we’re going to talk to Kate Duncan. And Kate is– I should ask, you are Kate Duncan? Or do you want to be Katherine Duncan or Dr. Duncan? Kate Duncan: Oh, … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …

… that know what they’re doing much better than I ever can at the level that we’re working. And so we do … they must be chemically protected in some way and lo and behold it’s this bacteria. And so the ANMG is depositing the … And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much …

… It will identify high-value partnerships among members that catalyze data flows and promote novel data … via designed and assembled physical DNA constructs that can then be functionally characterized.  Our metabolomics … accessible, AI-ready large-scale data repositories for genome information with analysis tools for mining and …