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PIs or co-PIs) who wish to include use-restricted data in publications, or who wish to redistribute data in any way … Proposals accepted before FY22 are transitioning away from producing use-restricted data. JGI proposals typically include multiple projects of different types which can span several …

… the University of Hawaii and moved there in the early ’60s from Berkeley to work on this new budding field of marine … genomics existed. This is before we’re even thinking of genes and connecting genes to molecules, which is something … what happens. Dan: Very cool. Well, the word you’ve used multiple times today is fun. And I know, from working with …

… prefers to be known among friends in natural products. He’s from Langebio in Irapuato, Mexico, and an incredibly bright … the regulation off, rather than negatively get rid of the genes from their genome. FRANCISCO BARONA-GOMEZ: Exactly … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

… into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes for bioenergy, nutrient … platform enables users to validate hypotheses generated from mining genomic data by designing and assembling …

… of sequence space:  The JGI generates reference genomes from diverse bacterial and archaeal lineages to improve … from isolates and single cells. This effort uncovers novel genes, protein families, and pathways, enhancing our understanding of evolutionary …

… cycling, and leads to the discovery of new molecules and pathways. The JGI Metabolomics Platform delivers rich metabolite profiles from diverse biological and environmental samples using … molecular profiles are generated for metabolites extracted from a variety of experimental samples, including organisms …

… climate and soil conditions around the globe to identify genes to improve our domesticated species.  The program … regions of interest and gene copy number variation across multiple genomes. It provides the ability to discover syntenic orthologs, generate publication quality graphics and explore pangenome views of …

… metabolic gene expression helps identify variants in yeast genes. The Science Scientists have developed a more nuanced … area in the DNA, to determine which targets might benefit from an intermediate level of expression. Similar to the results of the sugar-related tests, they pinpointed multiple genes that were previously missed in knock-out …

… week, we have our conversation with Professor Eric Schmidt, from the University of Utah. I’ve known Eric for a long time … really need to know how they’re made. You need to bring the genes into the lab, and you need to manipulate them in the … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …

… that support user analysis of biogeochemically-relevant pathways, enabling modeling of microbiomes based on … regulation, and noncoding RNAs in microbiomes. The insights from this work have the potential to drive innovations in … of complete or near-complete population genomes directly from the environment. These advances have led to …

The guest we have this week is Professor Cassandra Quave from Emory University, with joint appointments in the School … I think on COVID that we’re getting ready to submit for publication and have found some interesting hits for that as … compound is not the answer. Some cases, it’s actually multiple compounds acting in synergy which is scientifically …

Laboratory. Being a User Facility means that scientists from all over the world bring us big problems related to … so it’s some kind of – Is it a compound that helps them from drying out? Or… What is it? DAN:  Yeah I don’t know! … ALISON: Okay. We’re looking at a schematic of different pathways in a microbial cell, it looks like. It could be a …