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… got really high GC content, which means their base usage is skewed, and that can mess with some of the technology … So a lot of my work is as focused on insects As a host, and a little bit of my newer work is focused on … when you’re in a community? How is the microbiome being shaped by different types of secondary metabolites? How does …

… rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is … a version of the User Agreement between HHMI, your Host Institution and LBNL is required. NOTE:  If a PI … PI is named during the performance period, your Project Manager must be notified immediately. Either of these changes …

… Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all … at the end to get the compound expressed in a heterologous host strain. DAN UDWARY: Yeah, sure. That’s very similar to … easily can identify secondary metabolite pathways in metagenomes, which is still hard to do. We are mining a lot of …

… DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I talk to Roger … discovery, predominantly in diseases of importance to each host country. It was built very much on the foundations of … the idea that you could go internationally to do the next stage of your training and that there might be more to be …

… Data produced and released by the US Department of Energy … the need to have a limited and time-sensitive protection of certain types of data to support their use by those … PIs or co-PIs) who wish to include use-restricted data in publications, or who wish to redistribute data in any way …

… as user facility that aims to provide access to state-of-the-art DNA synthesis and assembly technologies to the … engineering pathways to function in heterologous hosts, by combining combinatorial synthesis, high-throughput … methodologies, and statistical frameworks for inferring genotype to phenotype associations. Research Team    …

… the Eloe-Fadrosh group focuses on using genome-resolved metagenomic approaches to identify and characterize genomic … develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial … ecosystem function.  The Environmental Genomics group also hosts the Viral Genomics group . Research Team    …

…   The JGI’s Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … essential for fundamental growth, provide critical advantages to the organisms producing them, and are often involved … Program targets the vast and underexplored reservoir of secondary metabolites produced by bacteria, fungi, algae …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … together to make small peptides. Those are fun, because the host organism can use whatever amino acids it has access to, … end, we took an approach that was kind of a simplified metagenome sequencing approach to pick this system apart.  …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … going to finish up by talking about the modern, post-golden age history of natural products discovery, and we’ll talk a … at naturalprodcast.com Special thanks, as always, to my co-host, Alison Takemura. <woohoo> If you like Alison, and want …

… As an Integrative Genome Science User Facility, the JGI … genome science capabilities to support BER's mission of achieving a predictive understanding of complex … the boundaries of the Plant, Fungal, Algal, Microbial, Metagenome, Metabolomics, Secondary Metabolites, and DNA …