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… and bioeconomy applications. The program provides high-quality, large-scale genomic data to advance microbial … of bacteria and archaea in their natural environments using single cell approaches. This includes linking strain-level genetic …

… required documentation here .  … You can request a JGI Single Sign On account at https://signon.jgi.doe.gov . This … ) Metagenomes and Single Cells: IMG/M   (citation: … for individuals associated with your proposal. Find our Publications Policy on our Data Policy & Support page.    … …

… felt kind of like training for a marathon by running at a high altitude! And a lot of us moved on to work in simpler … way – the RiPP way, is to make a protein using the normal cellular way of making proteins, with a ribosome. Then, some … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … two sequenced genomes of a Streptomyces , or gram-positive high GC organism.  Dan: Yeah, not a lot of natural product … of, better understand fundamentally what’s going on in the cell as it responds to its ocean environment. And as we …

… we want a chemist to study the ocean. And I didn’t find a single job advertisement. But one day, I decided to really … that the molecules out there would be toxic to cancer cells. And that started something big. Because at that time, … of Petri plates to watch what happens over time. And in the high-nutrient media, we saw all the same stuff, which are …

… was there for about three and a half years – I worked at a high school. And one of the things that I noticed is all the … parasite you really can’t grow well. You have to have it in cell culture. So we are going to see if we can express that … alone – I’m interested in pathogens. It’s just never a single microbe. And we have several recent papers and are …

… scientific discovery at the DOE Office of Science through high performance computing (HPC) and data analysis.  The DOE … the Letter of Intent; rather proposals are submitted in a single step. … The researcher then submits a proposal for … more customized analysis, the JGI also participates in publication of results. … Submission … More on Sequencing …

… functional genome annotation, improves understanding of the role small molecules play in diverse biological … samples, including organisms (e.g. microbes, fungi, plant), media in which they grow, as well as different types of environments (e.g. soil, lake).  A wide range of …

… sparked your interest, and you want to learn more, then I highly recommend David Hopwood’s book called  “Streptomyces … be successful. Right? Because we don’t – drugs are usually single molecules, they are not extracts. And so yeah, in … in ourselves and every living thing that we know of with cells, and so… So you can think of DNA as maybe being …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … the special, natural chemical compounds that you find in plants, fungi and bacteria, basically all living things. … great conversations that we’ve already recorded with some excellent scientists, and that’s probably how we’ll continue …

… had just not  been released yet. And there was also some transcriptome data. And my first task during that project … least a certain level of similarity. So if similarity was higher than a certain kind of volume. And if you do that, … sometimes correlated or anti correlated, also with other cellular functions in the same and as it was other bacteria …

The central mission of the JGI’s Genomic Technologies department is   ensuring … automation, and further advancing sequence applications, single cell genomics, DNA synthesis, and metabolomics.   … Deputy …