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… the scientific community as a user facility pioneering functional genomics to solve the most relevant bioenergy and … Science through high performance computing (HPC) and data analysis.  The DOE Systems Biology Knowledgebase ( KBase ) … next review cycle. All proposals undergo technical review by JGI staff as well as staff at the other participating …

… by bacterial or fungal metabolism by microbes, will have a functional role. We started from that. Evolution doesn’t … pathway is good for anything, it is if the final product is obtained. So let’s think about synthesis of an amino acid, … the feeling, we have is that if you have in these molecular networks, nodes that are not so highly diversified, for …

… and he has a project with the JGI to synthesize the genes for and explore the chemistry of quorum sensing … introduction in natural products, so I might just start out by asking you know how did you get started. I know you’re … that as a readout of activity. And I was really fascinated by that. And really more generally from undergrad the …

… cycle times from sample receipt to completion of standard analysis.  Raw data is provided for all sequencing products … submit raw sequence data to  SRA at NCBI once the standard analysis is complete. Raw metabolomics data is submitted to … ( IMG/M ), mapping 273/273 Metagenome Cell Enrichments Obtained by physical separation of a biologically relevant …

…   Metabolomics strengthens -omics technologies at the JGI by identifying the actual molecules present in an …  Through this identification, metabolomics enables functional genome annotation, improves understanding of the … products At JGI, in-depth molecular profiles are generated for metabolites extracted from a variety of …

… support researchers exploring how to convert sequence into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes for bioenergy, … a suite of tools to automate sequence design for assembly by Gibson, Yeast recombination and Golden Gate methods …

… like a lot of people hedge their way into natural products by starting out in synthesis and then discovering more-- … oftentimes will bind to receptors within biosynthetic gene clusters. Specifically, these are Tet repressors that … this is a really great question. I think that there is diffusion through the soil-- DAN: Sure. BETSY PARKINSON: --but …

… the natural world’s potential to address global challenges by exploring plants’ role in capturing carbon, detoxifying … supports the development of next-generation biofuels by studying perennial grasses and fast-growing trees as … and protein folding models, to improve the accuracy of functional predictions and speed up genome analysis. …

… genetic differences and then expanded on on that knowledge by doing a second postdoc with Yi Tang at UCLA and then kind … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever … where these strains coming from. Can you make any kind of association with the potential like, what’s the ecological …

… species.  Students collect fungi, sterilize tissue, isolate genes and more. The metadata then goes into iNaturalist. … The Mycocosm portal supports the annotation, comparative analysis, and distribution of fungal genome datasets. It … analyses. The Mycocosm user interface is designed for use by mycologists and researchers, facilitating the transition …

… along with their associated viruses and mobile genetic elements. Beyond exploring and characterizing … approaches to assess microbial activity across ecosystems.  By studying microbial communities and their interactions, … environmental sustainability, and many other applications. By understanding how microbes contribute to ecosystem …

… it’s really about what are they doing. And so it’s really functional genomics. And there’s a lot of sequencing based … to society really does give you the chance to build those networks of folks that you may not normally run into or … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …