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… to more easily integrate the expertise and capabilities of multiple Department of Energy Office of Science National … not only simplifies and streamlines this process, but enables scientists to conduct fundamental science … provides customized analysis, the JGI also participates in publication of results. … All proposals undergo technical …

… are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and … single-cell and spatial transcriptomics barcode-based genetics (RB-TnSeq), and computational genomics to better … of plant/environmental responses … Selected Publications … Research Team Alumni … For further details, …

… as user facility that aims to provide access to state-of-the-art DNA synthesis and assembly technologies to the … difficult to synthesize constructs such as those involving biosynthetic clusters, or high complexity combinatorial … We also develop methods for efficient QA/QC based on next-generation sequencing technologies including PacBio and …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … eat it, but it has a really fun and interesting biosynthetic pathway, and I’ll have to do a whole show on it … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …

… here today, and we wanted to talk to her about a whole list of things. So we have a Scripps background shared together, … need to say to you, but they’re unprecedented in the terms biosynthetic gene clusters and genome size. And they’re so … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … technology to help access complicated natural product gene clusters, and we’re all really excited about that, and … like JGI.  DAN: No, yeah, for sure. I mean, I can look at a biosynthetic cluster and sort of figure out what’s going on. …

… … DAN: You’re listening to the US. .Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … that can’t live without their host. They have no extra genes hanging around, they still dedicate 20-30% of their … published some great papers [on] recently – on evolution of biosynthetic gene clusters. And you and I have had some …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … and actually get to the DNA sequence – sequences for the genes that code for the proteins that produce secondary … of investigating those genes is that it was found that most biosynthetic genes are found clustered in the DNA. And so if …

… to current problems facing humanity. A major focus are biofuel feedstock species and plant-microbe interactions, … analyzed in a consistant computational framework. It enables cross-species comparisons, advancing DOE … the ability to discover syntenic orthologs, generate publication quality graphics and explore pangenome views of …

… … DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I talk to Roger … valuable. From my perspective, JGI has a large database of biosynthetic gene clusters and biosynthetic gene cluster … cluster and that we will see now, fairly soon, a fairly rapid collapse in the unknown fraction on either side there …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … After I got my undergraduate degree, which was in general biology, I joined the Peace Corps. And when I was … with, you know, weirdness in the sequence. You know, some clusters are not clustered…   NANCY: Right. I think that put …