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… … DAN: You’re listening to the US Department of Energy Joint … lot of like synthetic chemistry effort to create a bunch of novel compounds that actually didn’t pan out. DAN: And there … DNA sequence – sequences for the genes that code for the proteins that produce secondary metabolites. Do you …

… do engineering to improve the physical properties of a protein and make it easier to work with. But sometimes, what … So– yeah, with our collaboration with JGI , we basically designed a library that includes hundreds of different … from having a much more complicated ligand to wrestle with computationally and pyramidalization is that we need good …

… … DAN UDWARY: Hey, everyone! Welcome to the “Self Promotion … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever … like massive brownouts in California when you’re doing the computational analysis of metagenomes. DAN UDWARY: Well, the …

… … DAN: Hello, everyone, and Welcome back for Episode 14 of … we’re doing. And using these together along with all of our computational tools to really build out much more of an … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …

The Synthetic Biology lab is divided into a DNA synthesis production group and a … our efforts on integrating database mining and sequence design with scaling the production of large, difficult to … applications.  We are interested in:  characterizing novel enzymatic activities using phylogenomic driven …

… … DAN UDWARY: Hey everyone and welcome back to a new session of … or you could look at metabolism markers like phosphoprotein S6. So if there is a perturbagen present– DAN … in order to put them together to build pathways, to make novel compounds, or to find analogs. And that was Warp …

And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … easy to search for because there are patterns of domains, protein domains that you look for. And if you find those all … preferences A 10″ Simple Rules” article on increasing computational skills among biologists JGI CSP Proposal: …

… … DAN UDWARY: Hey, everyone. I’ve got a great episode for you … an exploration into the secondary metabolism of some more novel marine bacteria. You know, I first met Bill as a … molecules that bound inside the cells to tubulin, these proteins that allow the cells to divide. We found all sorts …

Research in the Eloe-Fadrosh group focuses on using … from uncultivated microbes and viruses. We develop computational approaches to sift through thousands of … Microbiology , 15032. 10.1038/nmicrobiol.2015.32 … Selected Publications … For further details, please reach out to the …

Metabolomics strengthens -omics technologies at the JGI by … system behavior.  Through this identification, metabolomics enables functional genome annotation, improves understanding … (LC-MS) based methods in combination with advanced computational analysis.   Overview of metabolomics products …

… … DAN: You’re listening to the US Department of Energy Joint … suggest you go back and check the first episode out. This one continues the introductory conversation between myself … often use primary metabolites as building blocks to produce novel molecules. And so we’ve got glycosides being made into …

… … DAN: Welcome back for episode 9 of Natural Prodcast. This … of sort of cooperative and collaborative science. It was designed to ensure equitable benefit sharing if any … anyway, to anywhere tackle that. So you’ve got to do it computationally. Right? So where do we start with that? …