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… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very … natural product producing organism, the Actinomyces, was completed in early 2000s. One of the major discovery from …

… factors and determine their binding sites across multiple genomes. Computational prediction of heterologous … computational analyses of BGC size and complexity, BGC sequence composition, metabolic similarity & compatibility, … signatures of horizontal gene transfer. … The SMC provides complete sequence and annotation data for secondary …

UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast– a podcast about natural … If we are only interested in that final product, which is completely potent and specific to the target we’re thinking … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

… is also reflected in the strongly biased representation of sequenced genomes in the public domain, the bulk of which belong to … … Research Interests … Former Lab Members … Selected Publications … For further details, please reach out to the …

Research in the Eloe-Fadrosh group focuses on using genome-resolved metagenomic approaches to identify and … develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial … Microbiology , 15032. 10.1038/nmicrobiol.2015.32 … Selected Publications … For further details, please reach out to the …

The central mission of the JGI’s Genomic Technologies department is   ensuring … users have access to cutting-edge capabilities to help advance their science by generating data in three overarching … through end-to-end automation, and further advancing sequence applications, single cell genomics, DNA synthesis, …

Breaking Bad, I guess. But no, you trained me in how to genome mine, so thank you for that. And you had to put up … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever … trying to understand that system is just not possible from– completely understanding the system is not possible from the …

… 2014), unearthing hundreds of thousands of new viral genomes and their predicted hosts (Nature 2016, Science … Nayfach S, et al. (2021) CheckV assesses the quality and completeness of metagenome-assembled viral genomes. Nature … Science 344(6186):909-13 … Research Efforts … Selected Publications … For further details, please reach out to the …

… group aims at improving our collective understanding of ecological and evolutionary parameters driving virus:host … al. (2019) Minimum Information about an Uncultivated Virus Genome (MIUViG).  Nature Biotech .  37 , 29–37 Roux S, et … abundant ocean viruses.  Nature . 537:689-93. … Selected Publications … For further information contact the Group …

… in the early 2000s called Ecopia, which was a very early genome mining company, back when DNA sequencing of natural … And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … called Ecopia was talking about a gene cluster a week. They completed a gene cluster per week. And that really got me …

… off today with my interview with the Director of the Joint Genome Institute and head of the Secondary Metabolites … that’s your turf.  NIGEL MOUNCEY: Yeah, great.  DAN: And completely free, right?  NIGEL MOUNCEY: It is completely … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …

… enzymes to do chemical reactions. Obviously, in my work, in genome mining, we have an awful lot of crossover, where us … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh … or something, but they confirmed that it had just been completely consumed. DAN UDWARY: Grad students need calories …