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A Letter of Intent is required. For accepted proposals, sequencing, synthesis, metabolomics and analysis will be … provides customized analysis, the JGI also participates in publication of results. … All proposals undergo technical … Following DOE approval, project managers negotiate project specifics with PIs (including JGI scientists as needed), and …

… into chemical energy — and its implications for carbon sequestration, renewable energy and agricultural … nodes. These families allow easy access to clade-specific orthology/paralogy relationships as well as … the ability to discover syntenic orthologs, generate publication quality graphics and explore pangenome views of …

… took an approach that was kind of a simplified metagenome sequencing approach to pick this system apart.  DAN:  And … sequence into an antibiotic that kills bacteria through a specific mechanism. Or whatever that peptide might be doing. … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …

The Fungal & Algal Program explores the vast diversity of fungi and algae to unlock their potential for bioenergy, … environmental sustainability, and bioproducts. By sequencing and analyzing the genomes of these organisms, the … … The Fungal & Algal Program harnesses cutting-edge sequencing technologies and advanced genomic analysis to …

… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … coding genes that are signatures for the presence of a specific type of biosynthetic gene cluster. And antiSMASH … are actually associated with these gene clusters, or to activity? So if you see a biological activity and you …

… before– or kind of around about when the first genome sequencing was done. But natural products– marine natural … you get more information. You can actually compare things accurately, and you get that community effort of finding out … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …

… are shaping each part of the metabolic network in each specific organism. Really, what matters is the forces that … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

The JGI’s DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of … Program aims to generate large datasets to explore sequence-function relationships, advancing the discovery of … nodes. These families allow easy access to clade-specific orthology/paralogy relationships as well as …

… and other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … Science 344(6186):909-13 … Research Efforts … Selected Publications … For further details, please reach out to the …

… the gut is, kind of. But not the same way this is designed specifically to house symbiotic bacteria. And so that has a … And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… in science.  DAN: Excellent, Yeah. OK, cool. So then what specifically about natural products? What got you in that … NIGEL MOUNCEY: Oh, sure. I think our legacy obviously is in sequencing.  DAN: Of course.  NIGEL MOUNCEY: Sequencing the … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …

… the list of open calls ; click on the call link to see specific details including project types supported, … proposals are subject to JGI policies on Data Release and Publication .   Except for applicants to the CSP New … for advice!      … The deliverables can range from raw sequence data to well-annotated assembled genomes to …