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… welcome back to Natural Prodcast, and this will be episode 11. This continues our little sprint on genome mining. In … of the common tools that genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and … project, and especially also about the more computational aspects of it, which I had found out during my Masters that I …

… that there was almost nothing. Now, this is back in the 1970s. So, I thought to myself, maybe I can use my … interesting chemistry? It seems hard to believe in retrospect. BILL FENICAL: Well, in 2021, absolutely hard to … that were different, different structure types. We started amassing a collection of marine bacteria. We also studied …

… following sites: Microbes: IMG (citation: https://doi.org/10.1093/nar/gkaa939 ) Metagenomes and Single Cells: IMG/M   (citation: https://doi.org/10.1093/nar/gkaa939 Fungi: Mycocosm (citation: … for individuals associated with your proposal. Find our Publications Policy on our Data Policy & Support page.    …

… Shining a Light: Advanced Photon Source Capabilities for FICUS Research describes the … SIP, Flux Balance analysis with metabolites, Isotope Ratio Mass Spectrometry, NanoSIMS, and other techniques. …

… in developing countries for research into various aspects of biodiversity, of which natural products chemistry … about the topic we cared about. And that gave us about 12,000 molecules. And that was enough for us to build a … the advent of two dimensional NMR and high resolution mass spectrometry. And so some of those stories percolate …

… quickly built up a great body of work, with interesting perspectives on evolution of natural products biosynthesis. I … to put it. So, I was at the Broad Institute in Cambridge, Mass. for a couple years before joining Warp Drive. And what … that’s really popped up at funding agencies and the popular news recently because a lot of soldiers in the Iraq and …

… taking a little bit of time off between my undergrad and my masters, but I ended up starting a master’s in plant … And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … else isn’t working on? Or that you bring a unique perspective too? And so I was fascinated by – we spend a lot of …

… Wisconsin. Like we discussed in the primer podcasts ( part 1 here , part 2 here , and part 3 here ), which you should … first started out the natural product community was almost 100% bacterial. Only people working in mycotoxins worked … do you check if they’re there? Like we always talk about 16S for bacteria, but we don’t talk about it so easily with …