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Natural Prodcast Episode 7: Ben Shen
… company Wyeth that introduced enediynes to the market in 2001 with a drug called Mylotag. Wyeth was later acquired by … So I wanted to ask you also about – because you were in the news recently – TSRI has acquired the Pfizer strain … genome, the genome predicts they often can produce around 30 – more than 30 compounds. So, this was a complete …
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Draft genome sequence of marine alphaproteobacterial strain HIMB11, the first cultivated representative of a unique lineage within the Roseobacter clade possessing an unusually small genome
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Rex Malmstrom
… of in situ growth rates and carbon consumption of SAR11 bacteria, the most abundant bacterial group in the ocean. … the arbuscular mycorrhizal symbiosis. Nature Plants 10, 673–688 Vyshenska et al. 2023. A standardized quantitative … photosystem to unicellular marine predators.  PNAS 116 (41), 20574-20583 Couradeau, J.S. et al. 2019. Probing …
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DOE Metrics
… (hours)**   Actual Total   Actual % Goal   FY 2026 Total   700.0     8,760     Q1 2026 175 313.081 179% 2,208 2,064 95.4% Q2 2026 175 243.806 139% 2,160 2,112 99.8% Q3 2026 175     2,164     Q4 2026 175     2,208   …
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Natural Prodcast Episode 4: Nancy Keller
… the primer podcasts ( part 1 here , part 2 here , and part 3 here ), which you should be able to find earlier in the … first started out the natural product community was almost 100% bacterial. Only people working in mycotoxins worked with … on microbiomes they only talk about the bacteria. My god! 30% of our gut microbes are fungi. It’s really frustrating …
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Tanja Woyke Elected to American Academy of Microbiology
… the 68 new Fellows in the Class of 2020, selected from 118 nominees. The selection process for AAM Fellows is based … As a result, the giant virus protein space grew from 123,000 to over 900,000 proteins, and virus diversity in this … the AAM Fellows in this cohort. Go here for the full AAM news release. Woyke is also one of the organizers for the …
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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
… launched a concerted SOD defensive campaign beginning in 2000. In an effort to fingerprint the pathogen and trace its … All told, the disease has accounted for upwards of $30 billion in losses , including the death of tens of … 1;313(5791):1261-6. doi: 10.1126/science.1128796 Science News of the Day: Stokstad E. Genetics. Genomes highlight …
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Finding the Fermenters
… researchers recently compiled a list of with more than 8,300 organisms from multiple sources, including the U.S. … interactive browser – contains the phenotypic records of 8,350 organisms along with 4,355 genomes and 13.6 million … Narrative for Porphyromonadaceae sp. W3.11 genome on KBase …
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Mining Metagenomes for Cas Proteins
… is now at Tel Aviv University. The Cas14 proteins are ~400–700 amino acids (aa) in size, half that of previously known class 2 CRISPR enzymes that are typically 950—1400 aa. They were initially identified by searching for … the US Department of Energy under contract no. DE-AC02-05CH11231. The work was supported in part by grants from the …
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JGI announces 2025 Functional Genomics awardees
… and biotechnology innovation. Below find a list of the 11 researchers accepted for 2025.  Proposals are accepted …
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Natural Prodcast Episode 19: Bill Fenical
… underwater. But thankfully that worked out. And I spent 30, 40 years diving all over the world and bringing samples … And that means that you have to provide up to maybe 100 grams of the natural product. And that was, for us, very … chemistry. And I’ve studied microbiology for about 25, 30 years. And I can actually go give a talk at ASM [The …
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Streamlining Regulon Identification in Bacteria
… sequencing, they were able to identify the target genes of 11 sigma factors in Streptomyces coelicolor . The Impact As … Prior to this most recent study, only 12 sigma factors and 200 genes (or 209 sigma factor-target gene pairs) had been … 18, with the number of factor-gene pairs almost doubling to 399. Two of the 11 sigma factors addressed in the study were …
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