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… the story of a giant metagenome assembly from Wisconsin’s Lake Mendota. In this episode: a look at the supercomputing …

DAN UDWARY: So it sort of does it work in the first place for instance? Is it useful? ALISON NARAYAN: I like to think every enzyme is a little snowflake. JACKIE WINTER: To treat it so it’s a delicate … ancestral sequence reconstruction”,  PNAS.  2023,  120, e2218248120. doi : 10.1073/pnas.2218248120 …

… sponge chemistry and looking for active compounds and pharmaceuticals. ALISON:  Okay, and he was looking at how the … But in order to use it, it’s got to be surgically placed into your spine into your – intrathecally – and then … this from a field where everyone’s working in their own space to a common framework where we hold the problems in …

… would take the pick and get us about two feet under the surface and then we would take our two foot core. And so that’s … I’ve always wondered if deserts or maybe glaciers are places where there are less nutrients there, so there would be … look for. And if you find those all together in the same place on the chromosome then you’ve definitely found a …

DAN: Well, today, I think we’re more or less in the same place we’ve probably been since the last decade. We have a lot … sequencing going on, especially at the JGI and in other places. And we have many, many 10s – or probably at this point … so that makes actually just the sequencing in the first place, difficult to do. So if we can make more technology, if …

… to thinking of, like someone crashing at someone else’s place. OK. That helps me. Dan Udwary: Congratulations. Alison … whether that meeting was going to happen in the first place. And yet everything got canceled due to the pandemic. … you to actually locate a gene cluster family in feature space because a gene cluster is then represented as a feature …