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… our series on a giant metagenome assembly from Wisconsin’s Lake Mendota. In the last two episodes, we’ve covered the … this project. But every part of this project depends on lakewater samples — so this episode is a look at how …

… the story of a giant metagenome assembly from Wisconsin’s Lake Mendota. In this episode: a look at the supercomputing …

DAN UDWARY: So it sort of does it work in the first place for instance? Is it useful? ALISON NARAYAN: I like to think every enzyme is a little snowflake. JACKIE WINTER: To treat it so it’s a delicate … ancestral sequence reconstruction”,  PNAS.  2023,  120, e2218248120. doi : 10.1073/pnas.2218248120 …

… sponge chemistry and looking for active compounds and pharmaceuticals. ALISON:  Okay, and he was looking at how the … But in order to use it, it’s got to be surgically placed into your spine into your – intrathecally – and then … this from a field where everyone’s working in their own space to a common framework where we hold the problems in …

… would take the pick and get us about two feet under the surface and then we would take our two foot core. And so that’s … I’ve always wondered if deserts or maybe glaciers are places where there are less nutrients there, so there would be … look for. And if you find those all together in the same place on the chromosome then you’ve definitely found a …

DAN: Well, today, I think we’re more or less in the same place we’ve probably been since the last decade. We have a lot … sequencing going on, especially at the JGI and in other places. And we have many, many 10s – or probably at this point … so that makes actually just the sequencing in the first place, difficult to do. So if we can make more technology, if …