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… of their synthases so that we can start to use the DNA sequence to predict or just understand better the … it’s a little intimidating. DAN: Unfortunately Alison is no longer with us… She’s alive! She just doesn’t work for JGI … the answer would be that there’s actually a great deal of diversity within these methanotrophs for example, that are …

… through isolation and genome sequencing of new fungal species.  Students collect fungi, sterilize tissue, isolate … the Arizona Genomics Institute where high molecular weight DNA is extracted from samples, which is then sent to the JGI … to biological inference and understanding of fungal diversity, ecology, and potential applications. … The …

The Joint Genome Institute's DNA Synthesis Platform capabilities support researchers … tools for workflow management and novel automations for DNA design, assembly and analysis Overview of synthesis products The JGI DNA Synthesis platform enables users to validate hypotheses …

… which was a very early genome mining company, back when DNA sequencing of natural product pathways was hard and … ranging conversation, and we could have gone on for a lot longer than we did, and I can say without reservation that … actinomycete-specific approaches. And you can enrich for rare actinomycetes by doing some tricks. Treating them with– …

The Synthetic Biology lab is divided into a DNA synthesis production group and a synthetic biology applications group. The DNA synthesis and assembly group: Our production group … facility that aims to provide access to state-of-the-art DNA synthesis and assembly technologies to the broader …

… with animal metabolism itself, and it’s really amazing what diversity there is in animals. I think, even despite the … one of the most common animals in the ocean. They’re really species-diverse. I lost track actually of the number. But, … and so on that we can consult in designing pieces of DNA that we can use to test these issues. The second area …

… niche in chemical enzymology. So, we talked about her JGI DNA synthesis project to explore the chemical capabilities … made it onto our list is because we wanted to have diversity. And so we wanted a profile across that protein … take this data. One that I’ll point out specifically is a website created by Nick Turner’s lab. So Nick Turner is at …

… using advanced sequencing technologies to explore microbial diversity — with an emphasis on bacteria and archaea, and … metatranscriptomes, with over 15 million viral genomes and fragments. … GOLD is a web resource for comprehensive access to information …

Plants are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including … multipartite phenomenon in additional plant and bacterial species of bioenergy importance. … We are using cutting-edge …

… the show notes, which you can always find through the JGI website at  naturalprodcast.com . Finally, I’ll just mention … our work in sequencing and genome mining with using DNA synthesis to express clusters metabolomics to be able to … A few examples of those are obviously expanding the diversity of known secondary metabolites and their …

… we’re thinking they’re obligate marine. There’s so far no species or no strains known that really grow in freshwater. … see. So it doesn’t seem to be a correlation between biodiversity in taxa and biodiversity in secondary metabolites. … to hear from you. We have projects in genome sequencing, DNA synthesis, transcriptomics, metabolomics, and natural …

… with Berkeley Lab, a process which can take 6 months or longer to obtain with no guarantee of approval.    JGI staff … data to well-annotated assembled genomes to synthesized DNA constructs to metabolomics data, depending on the … activity. A few examples include: Convention on Biological Diversity Nagoya Protocol on Access and Benefit Sharing …