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… I talked about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, … of those 150 plus people. I have to admit, as a PI, I’m no longer impressed by that number. But as a postdoc, I … family would be a set of gene clusters across different species, which all encode the production of either the same …

… – problems that might need special technology for DNA sequencing, genomics, metabolomics, and synthetic … a molecular biology term. We recorded the Primer as a much longer conversation, which I cut into more digestable … at MIT, and I studied microbial ecology. I studied Vibrio species in the ocean, so heterotrophic bacteria. Now, we …

… The Fungal & Algal Program explores the vast diversity of fungi and algae to unlock their potential for … and advanced genomic analysis to explore the rich diversity of fungi and algae. These organisms play a … and environmental sustainability. Fungi, with million species, are essential for ecosystem functioning — …

… through isolation and genome sequencing of new fungal species.  Students collect fungi, sterilize tissue, isolate … the Arizona Genomics Institute where high molecular weight DNA is extracted from samples, which is then sent to the JGI … to biological inference and understanding of fungal diversity, ecology, and potential applications. …

… which was a very early genome mining company, back when DNA sequencing of natural product pathways was hard and … ranging conversation, and we could have gone on for a lot longer than we did, and I can say without reservation that … actinomycete-specific approaches. And you can enrich for rare actinomycetes by doing some tricks. Treating them with– …

… niche in chemical enzymology. So, we talked about her JGI DNA synthesis project to explore the chemical capabilities … of flavin independent monooxygenases with the help of JGI’s DNA synthesis grant. And that having a whole panel of these … made it onto our list is because we wanted to have diversity. And so we wanted a profile across that protein …

… with animal metabolism itself, and it’s really amazing what diversity there is in animals. I think, even despite the … one of the most common animals in the ocean. They’re really species-diverse. I lost track actually of the number. But, … and so on that we can consult in designing pieces of DNA that we can use to test these issues. The second area …

… tools for workflow management and novel automations for DNA design, assembly and analysis Overview of biodesign … mining genomic data by designing and assembling physical DNA constructs that can then be functionally characterized.    We provide custom DNA constructs:  Individually arrayed constructs, up to ~150 …

… with Berkeley Lab, a process which can take 6 months or longer to obtain with no guarantee of approval.    JGI staff … data to well-annotated assembled genomes to synthesized DNA constructs to metabolomics data, depending on the … activity. A few examples include: Convention on Biological Diversity Nagoya Protocol on Access and Benefit Sharing …

… The Synthetic Biology lab is divided into a DNA synthesis production group and a synthetic biology applications group. The DNA synthesis and assembly group: Our production group … facility that aims to provide access to state-of-the-art DNA synthesis and assembly technologies to the broader …

… we’re thinking they’re obligate marine. There’s so far no species or no strains known that really grow in freshwater. … see. So it doesn’t seem to be a correlation between biodiversity in taxa and biodiversity in secondary metabolites. … to hear from you. We have projects in genome sequencing, DNA synthesis, transcriptomics, metabolomics, and natural …

… the required capabilities, they then ship samples—such as DNA and RNA for sequencing—to JGI. Users are responsible for … assemblies or differential gene expression results. For DNA synthesis projects, JGI ships physical materials like … which it becomes publicly available. If you're requesting DNA synthesis from JGI, there's also a material transfer …