Search

… is to lead AI-driven genomic innovation to advance biotechnology.   … by supporting the scientific foundations that drive biotechnology and biomanufacturing innovation. The JGI … processes that enable cost-effective energy generation and innovative materials production. Through collaboration with …

… sustainability, and many other applications. By understanding how microbes contribute to ecosystem … the Program helps drive innovations that could advance our understanding of Earth’s ecosystems. … One of the key goals of the Program is to develop a deeper understanding of microbial community assembly and microbial …

… And at the time, nobody was interested in licensing that technology or doing anything with it. So I was kind of … mammalian systems. But it allows us to assay on a single cell level against cell lines and against primary cells … in everninomicin and analogs of that, you’re really understanding one specific biosynthetic pathway. I guess how …

… systems, linking them with genomic data to enhance our understanding of genome science, organisms, and ecosystems … development of high performance plants and microbes, and understanding microbiome interactions. The  insights derived … The Metabolomics Program is focused on understanding the critical roles of metabolites in living …

… through the stories I told you about geosmin, which is a bacterial sacred metabolite, and ergot alkaloids come from … of secondary metabolism in the environment, and, sort of, understanding – like we’ve talked about – how bacteria or … more and more and more things.  ALISON: I see. Yeah, that technology has been really crucial.  DAN: Yeah, yeah. The …

… (BGCs), advancing pathway analysis, optimization of cell- and cell free-based expression platforms, tools and data for … Development of cell-free based expression platforms: Only 10-20% of BGCs … conditions by their native hosts. We are developing cell-free based systems to express BGCs that alleviate the …

… earlier. You talked about competition in the field. And my understanding is that, well, it was very competitive when I … that the molecules out there would be toxic to cancer cells. And that started something big. Because at that time, … that is used to degrade proteins, peptides, that are signaling, normally doing some signaling activities in the …

… in Nature and Medicine.” It’s obviously focused more on the bacterial side of the field, and it’s a little hard to find … so, the reason I bring this up is because, you know, as the technology developed and molecular biology developed to the … in terms of – well it’s really simple in terms of understanding it because it’s an assembly line. You just go …

… access to JGI and the Molecular Foundry is granted with the understanding that the resulting work will be published. JGI …

… from genomic sequences to biological inference and understanding of fungal diversity, ecology, and potential …

… granting access to diverse datasets that deepen our understanding of how organisms interact with each other and … genomes to metagenomes to systems-level modeling and understanding. JGI and KBase are designated DOE Office of …

… actually can learn just by really digging into the data and understanding what’s going on there. And now, that’s all I … talking about what it would take to expand on the existing technology. And a lot of that was around chemical identification technology, mass spec, NMR. And we talked a little bit about …