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… through the stories I told you about geosmin, which is a bacterial sacred metabolite, and ergot alkaloids come from … of secondary metabolism in the environment, and, sort of, understanding – like we’ve talked about – how bacteria or … more and more and more things.  ALISON: I see. Yeah, that technology has been really crucial.  DAN: Yeah, yeah. The …

… granting access to diverse datasets that deepen our understanding of how organisms interact with each other and … genomes to metagenomes to systems-level modeling and understanding. JGI and KBase are designated DOE Office of …

… to the host country. And it had a huge mission to perform technology transfer and infrastructure development in these … in lots of areas, we would like to do a better job of understanding gas phase reaction mechanisms. We would like … carefully at these as being candidates siderophores. Or for cell-cell signaling or for, you know, other other roles …

… (BGCs), advancing pathway analysis, optimization of cell- and cell free-based expression platforms, tools and data for … Development of cell-free based expression platforms: Only 10-20% of BGCs … conditions by their native hosts. We are developing cell-free based systems to express BGCs that alleviate the …

… earlier. You talked about competition in the field. And my understanding is that, well, it was very competitive when I … that the molecules out there would be toxic to cancer cells. And that started something big. Because at that time, … that is used to degrade proteins, peptides, that are signaling, normally doing some signaling activities in the …

… in Nature and Medicine.” It’s obviously focused more on the bacterial side of the field, and it’s a little hard to find … so, the reason I bring this up is because, you know, as the technology developed and molecular biology developed to the … in terms of – well it’s really simple in terms of understanding it because it’s an assembly line. You just go …

… actually can learn just by really digging into the data and understanding what’s going on there. And now, that’s all I … talking about what it would take to expand on the existing technology. And a lot of that was around chemical identification technology, mass spec, NMR. And we talked a little bit about …

… capture microbial and viral diversity, leading to a better understanding of microbial communities and ecosystem … genomes, which is of fundamental value to improving our understanding of microbial ecology and metabolism by … (ANI), which provides a computationally effective method of understanding the microbial makeup of environmental samples. …

… mission science projects, this initiative aims to encourage innovative research exploiting a diversity of capabilities. …

… back together. So a lot of sequencing depends on Illumina technology, which is usually what we refer to as “short … for many millions, sometimes billions, of years. And understanding how those changes that evolution brokers are … of the opinion that on the geological timescale, that most bacterial natural product systems evolved, you know, a …

… intended to accelerate basic research in the development of cellulosic ethanol and other biofuels, advancing the federal … high-yielding feedstock plants, using advanced genetic technology to accelerate the domestication of perennials. … building on an existing data set, or the refining of new technology (e.g., single-cell genomics; metagenomics, …

… in a microalgae. There were four genes there. Not like a bacterial gene cluster, but they were still clustered in the … NOAA has funded to really look at how we can use our gene technology to predict when blooms are going to happen, that … in a laboratory. And so, for us, we’re fascinated by understanding the logic of nature and how it can control …