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… we get to present our conversation with Marnix Medema , from Wageningen University in the Netherlands. Marnix is … some of these enormous genes that encode these very large enzymes. And I was like, OK, wow, these are really cool. And … is definitely the most comprehensive set of tools for identifying gene clusters. There’s nothing that is quite as …

… maybe it’s a new culture of a new bacteria that you pulled from the soil, maybe it’s, you know, we talked about … lot of like synthetic chemistry effort to create a bunch of novel compounds that actually didn’t pan out. DAN: And there … Right. Yeah. DAN: Alright, so a subset of proteins are enzymes. Enzymes are proteins that do chemical reactions. …

… The guest we have this week is Professor Cassandra Quave from Emory University, with joint appointments in the School … use successfully, hopefully, in the future even more so as novel therapies. And that’s how I got on that path of … but perhaps the idea of running off into the forest and identifying different plants and bringing them back is not …

… our interview this week is with Professor Brian Bachmann from Vanderbilt University’s Chemistry Department, where he … what led me to natural products. So after realizing that enzymes were specific for their substrates, that you … in order to put them together to build pathways, to make novel compounds, or to find analogs. And that was Warp …

… over our interview with Dr Elizabeth (or Betsy) Parkinson from Purdue University. She’s in the Department of Chemistry … But on the other hand, we're also really interested in enzymes to do some of the reactions that chemists find … very important in that peptidoglycan cross-linking. These enzymes show a lot of similarity to them in the primary …

… and shipping; JGI will handle all subsequent processing from that point. JGI provides users with various outputs … publicly available. If you're requesting DNA synthesis from JGI, there's also a material transfer agreement that’s … project with Molecular Foundry once you have what is needed from JGI.   …

… studied chemistry, because she switched her degree program from geography to chemistry. So we were both enrolled as … currently exist. We looked at chemistry, so it’s really novel. And they’re just really exciting. And it really kind … metabolomics, and natural products in plants, fungi, and microorganisms. If you want to collaborate, let …

… regulation, and noncoding RNAs in microbiomes. The insights from this work have the potential to drive innovations in … Exploration of phylogenomic novelty: Advances in metagenomic sequencing, assembly and … of complete or near-complete population genomes directly from the environment. These advances have led to …

… in particular to study inter-organismal interactions. Novel approaches are being explored to predict microbial … of sequence space:  The JGI generates reference genomes from diverse bacterial and archaeal lineages to improve … from isolates and single cells. This effort uncovers novel genes, protein families, and pathways, enhancing our …

… tough cell wall materials that keep microbes — and the enzymes that would be produced by microorganisms — out,” … loads of tough plants. Thanks to gut microbes — namely, anaerobic fungi — these animals are able to pry apart plant … it’s possible that fungal communities — or enzymes from fungal communities — could pave the way for many …