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… of a gene that you knew was probably biosynthetic that encoded for some secondary metabolism, then you would … And so when I came into graduate school, I worked on that project. And it was working exactly that same kind of way, … it has a really interesting biosynthetic pathway because fungal genes are cool. And if you like fungal genes, you …

… the pharmaceutical industry. He holds joint appointments as Fungal and Algal Program Head at the JGI, a Senior Scientist … of California, Berkeley. He contributed to the Human Genome Project and led annotation and analysis of diverse … from protists to plants. In 2009, he launched the JGI Fungal Genomics program which resulted in over 2500 fungal …

… in his science. And he was working with some really cool projects at that time. So I was pretty stoked to be able to … linear, like Streptomyces , but circular. 10% of the genome encoded natural product pathways. Dan: Yeah, that’s kind of … with, and, turns out, that high repeat sequence area encoded a polyketide synthase, with many modules of high …

… The JGI Project Management Office carries out a number of activities to facilitate world-class science. DOE JGI Project Managers collaborate with users to develop project requirements, define the scope of work and outline …

… what we know is they’re quite selective in some way for antifungal activity. They are also, some of them, are … and helping to concentrate it. But that’s the next project.  DAN: Thanks.  ALISON: We had talked a little bit … be able to find genes in the organism in its sequence that encode for that biosynthesis. But sometimes you have to know …

… help solve energy and environmental challenges. The 1KFG project represents affiliations at over 180 organizations in … countries. (Graphic: Neil Byers) The JGI launched the 1000 Fungal Genomes (1KFG) Project through a 2012 Community … of Oregon State University led the effort to sequence 1000 fungal genomes to create two reference genomes for all fungi …

… to DOE for final approval.  Following DOE approval, project managers negotiate project specifics with PIs (including JGI scientists as … For sequencing projects, once work is under way, raw sequence data is … with applicants and others who might be interested in the project are coordinated through JGI’s Project Management …

… sequencing, synthesis, and metabolomics at the JGI for projects of relevance to Department of Energy (DOE)  Mission … umbrella of our CSP: The Large Scale call is for expansive projects that leverage a range of JGI capabilities, and also … New Investigator call is for PIs who have never led a JGI project, and the Functional Genomics call is for projects …

… the DNA Synthesis Science User Advisory Committee, the Fungal and Algal Program User Advisory Committee, the …

… drive innovations that cross the boundaries of the Plant, Fungal, Algal, Microbial, Metagenome, Metabolomics, …

…   Revisit past projects …

… Past projects …