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Right, because they’re so reactive. BEN: …going back to the 1950s. But the structure of which was not known until the … as a new type of medicine that will open up a new year for targeted anti cancer drug discovery. DAN: Yeah, … drug conjugates, abbreviated as “ADC”, was approved in the year 2000, and utilize the enediyne as the payload. We call …

… advisor.  Brad: Oh my goodness. Those were good years, Dan!  Dan: For too many years. Brad: And now look, you’re like, famous. Dan: Famous? … natural products. And was at the university for over 40 years. There were four of us as kids in the family. I was …

… 2024 was a year of first, including the flagship internship program …

… white papers. Applicants may submit up to two proposals per year (but may be listed as co-PI on an unlimited number of …

… been in – working in secondary metabolism for almost 20 years now. Which when I did the math, that was a surprise to … professor at the University of Rhode Island for a couple of years before I left that to join a biotech startup. And … about that.  DAN: Yeah, you know it took several hundred years for us to even understand that it was maybe natural …

New 5-year strategic plan outlines how the JGI will advance the … Joint Genome Institute (JGI) has released its newest 5-Year Strategic Plan: Innovating Genomics to Serve the … on existing strengths to accomplish this vision.” Over a year and a half, Visel drove the effort, comprised of …

… natural product molecules might actually get to market in a year. And that would be a good thing. That would be high. … has evolved over, you know, probably – possibly billions of years. And so it is pretty used to the way that the assembly … We don’t have – we can’t go back, you know, millions of years to find the precursor sequences. Those species are …

… project by watching Amanda Hurley’s presentation from the 2019 JGI Genomics of Energy & Environment Meeting.] He’s also … was at the Broad Institute in Cambridge, Mass. for a couple years before joining Warp Drive. And what kind of pushed me … time. And yeah, I mean, that was let’s see, maybe 5,6,7 years ago, and I’ve – I haven’t looked back. ALISON: So you …

… that, I wanted to tell a quick story. Looking back, the year was probably 2010, 2011, I was a, uh- actually, I’ve … time. So they had actually sequenced the genome a number of years earlier as one of the first Streptomyces genomes that … web version of antiSMASH as well. Initially, in the first years of antiSMASH, we only made updates for every NAR paper …