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… been in – working in secondary metabolism for almost 20 years now. Which when I did the math, that was a surprise to … professor at the University of Rhode Island for a couple of years before I left that to join a biotech startup. And … about that.  DAN: Yeah, you know it took several hundred years for us to even understand that it was maybe natural …

… natural product molecules might actually get to market in a year. And that would be a good thing. That would be high. … of molecular biology got more sophisticated around the 80s and the 90s. And so we started to be able to explore DNA … has evolved over, you know, probably – possibly billions of years. And so it is pretty used to the way that the assembly …

… was at the Broad Institute in Cambridge, Mass. for a couple years before joining Warp Drive. And what kind of pushed me … time. And yeah, I mean, that was let’s see, maybe 5,6,7 years ago, and I’ve – I haven’t looked back. ALISON: So you … new. I joined as the lead on the genomic side about 6, 7, 8 months ago, and our metabolomics expert was around the …

… that, I wanted to tell a quick story. Looking back, the year was probably 2010, 2011, I was a, uh- actually, I’ve … time. So they had actually sequenced the genome a number of years earlier as one of the first Streptomyces genomes that … then I contacted a number of PIs, and in the end, I think 80 research groups from around the world contributed with, …

… notable research and scientific collaborations in 2018. The cover is an image of Mono Lake, a saline soda lake …

… houses Vibrio fischeri, it’s one strain and there have been years and years and years about 35-ish years, I think, now, studying Vibrio …

… the Department of Energy (DOE) colleagues. “At that time (1986) 98% of the human genome was thought to be junk DNA, so … Lab. Like the mural, the JGI’s accomplishments over 25 years span a broad, colorful range. Behind every genomic … with a single proposal. From the vantage point of JGI’s 25 years fueling discovery, Anderson looked toward the JGI’s …

Biotechnology (SIMB) Natural Products meeting earlier this year. And today we have our conversation with Professor … NARAYAN: And the planet was hotter millions and billions of years ago. DAN UDWARY: Like, really early on. [LAUGHING] … run things in like little Eppendorf tubes, or in 96, or 384 well plates. But then the fun really starts when you’re …

… the content produced by microbes the result of millions of years of evolution. And if we could actually link terms to … conditions, unless it happens on the long term, millions of years. So interesting case. It could well be that some of … that particular pathway. So all these BGCs encode between 80-90% of all known genes. Or genes that you can put a name …

… of the research that you’ve been doing the last couple of years. And I really want to make sure that we talk about … plants’ chemistry ever since the isolation of morphine, 1870 or something like that. And so people were well aware of … But thankfully that worked out. And I spent 30, 40 years diving all over the world and bringing samples into …