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… as a new type of medicine that will open up a new year for targeted anti cancer drug discovery. DAN: Yeah, … drug conjugates, abbreviated as “ADC”, was approved in the year 2000, and utilize the enediyne as the payload. We call … if you are a microbiologist in the 40s, how do you classify a strain? You look at it and this is the 40s – you don’t …
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… scientific approaches to these challenges. Our homepage video includes external footage from: University of … for JGI resources and are engaged in active projects—each year. In addition, several thousand data users worldwide … program in the DOE’s Office of Science. In December 2019, the JGI relocated to the newly-built Integrative …
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… the IP & Science arm of Thomson Reuters, has released their 2019 list of Highly Cited Researchers , which includes 10 affiliated with the JGI . The 2019 list focused on Highly Cited Papers, defined in the … were involved in that were reported on over the last year: Kerrie Barry and Jeremy Schmutz worked with a …
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… chemical biology, a lot of which people classify as tool building. So I worked with a really great guy … nice summer day in Seattle I think this was like 2013 or 2014. And antiSMASH — I know you’ve interviewed Marnix … AARON PURI: Sure. Great. I have a job for a couple of years. But the other thing that we can do that we’ve been …
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Foster and too many others to name at JGI for the last two years or so. SMC is now released and ready for the public to … about natural products. So in Brad’s lab, I worked on identifying and characterizing haloperoxidases from bacteria. And … you go to the website, which is smc.jgi.doe.gov , the stats page is showing me that right now we have just over a …
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… advisor. Brad: Oh my goodness. Those were good years, Dan! Dan: For too many years. Brad: And now look, you’re like, famous. Dan: Famous? … cool because the work has gone so much more than just identifying genes to that toxin, but it’s opened up this whole …
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… (VEGA) … The JGI is represented at conferences year round; find out where our researchers will be …
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… we are today, recording today. BRIAN BACHMANN: Yeah, in the year 2000. And I was trying to figure out what to do with … out gene clusters maybe once a month at most. Maybe twice a year, a full gene cluster would come out. And it was a very … how much blood, sweat, and tears went into trying to identify that you had the right cluster before you sent it out for …
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… then you need to go back to your extract and try to purify the molecule that’s causing that test to be successful. … natural product molecules might actually get to market in a year. And that would be a good thing. That would be high. … has evolved over, you know, probably – possibly billions of years. And so it is pretty used to the way that the assembly …
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… of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary metabolism … that, I wanted to tell a quick story. Looking back, the year was probably 2010, 2011, I was a, uh- actually, I’ve … time. So they had actually sequenced the genome a number of years earlier as one of the first Streptomyces genomes that …
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