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… of it. So it wasn’t only chemistry or only biochemistry or genetics. It was also ecology. It was also evolution. It was … I could see a certain time span within these biosynthetic gene clusters. There’s gene fusion going on, and then I … a marine actinomycete bacterium. So they look kind of like fungi but also make these mycelia. They kind of look like …

… opportunities for breakthrough discoveries and catalyzing a major transition of biology into data science.  Research in … include exploration of the global diversity of alternative genetic codes (Science 2014), unearthing hundreds of … Science 2017, Nature Microbiology 2018), discovery of new genes with important biotechnological applications (e.g., …

… Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire chromosomes, … the program enables the design and synthesis of complex genetic pathways and biosystems. It The program fosters … in advancing functional genomics, focusing on developing genetic systems that can address global energy and …

… genomics existed. This is before we’re even thinking of genes and connecting genes to molecules, which is something that, you know, we … metabolomics, and natural products in plants, fungi, and microorganisms. If you want to collaborate, let …

… of plant evolution and adaptation.    Understanding how genes are regulated is like deciphering the complex wiring … Traditionally, mapping this intricate network of regulatory “switches” in plants at a large scale was akin to … — and integrated these data with single-cell gene expression maps. Together, the scale of data enabled by …

… can see these beautiful nudibranchs, these sea slugs, and finding out that there’s a chemical story and natural … see as the overall “theme” of your research? I know you’ve generally worked in various marine organisms. Except during the time that we worked in fungi. But what do you see as the overall theme of your …

… analysis to date of the modified DNA base 5mC variations in fungi. The Science Changing an A, C, T or G in a genome … that unlike most flowering plants and animals, fungi lack gene body methylation. The analysis revealed that 5mC in … – similar to the MAC clusters for 6mA), rather than in genes, which suggests that 5mC may play a role in genome …

… focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One such … at environmental cells that are from candidate phyla, major branches in the phylogenetic tree without cultivated representatives. The “Great … Phylogenetic diversity estimates show that the gap between …

… The focus of this group, in recent years, has been to bring generalizable technologies to bacteria, yeasts and algae previously with little to no genetic tools enabling heterologous expression and functional exploration.  The developed …

… simply unpalatable. And we know that this is one of the major adaptations in the ocean. So it took a while to … we need to find out what that impact is. So, we started finding that the molecules out there would be toxic to … the most effective application, of marine molecules in general. DAN UDWARY: Maybe can you explain to our audience …

… and ‘omics capabilities to enhance understanding of gene and genome function, particularly those not readily … and track record of the applicant.  Learn about the general review process or find details on the internal … For general questions, please reach out to Christa Pennacchio, …

… The majority of JGI projects come from the user community. Find … address, click the “Request email change” link. This will generate an email that will go to an administrator to … and have not been validated by the JGI, but are provided as general guidance. … Genome Portal . The PI and all authorized users can also generate various reports. Access the reports by searching …