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… which was a very early genome mining company, back when DNA sequencing of natural product pathways was hard and … episode with her in the near future where we can dive into that. And I’m also dying to talk in more detail about … in everninomicin and analogs of that, you’re really understanding one specific biosynthetic pathway. I guess how …

… Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire chromosomes, … the program enables the design and synthesis of complex genetic pathways and biosystems. It The program fosters … Program aims to generate large datasets to explore sequence-function relationships, advancing the discovery of …

… question. Kate, can you tell me the story of how you got into secondary metabolites? Kate Duncan: So I always liked … before– or kind of around about when the first genome sequencing was done. But natural products– marine natural … Dan Udwary: Yeah. Kate Duncan: So they’re also incredibly adaptable. I think there has been some examples of real …

… granting access to diverse datasets that deepen our understanding of how organisms interact with each other and … access and analyze data on scales ranging from single genes and individual genomes to metagenomes to systems-level modeling and understanding. JGI and KBase are designated DOE Office of …

… partnerships in developing countries for research into various aspects of biodiversity, of which natural … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire … in lots of areas, we would like to do a better job of understanding gas phase reaction mechanisms. We would like …

… marine natural products chemist, Richard Moore, and get into seaweed, robots, algae, and biocatalysis — and he makes … then genomics happened. Dan: Yeah, I did my first genome sequence with you. Brad: That’s right,  Dan: JGI did it in … in a laboratory. And so, for us, we’re fascinated by understanding the logic of nature and how it can control …

… So maybe we could start with that background – what got you into secondary metabolism, besides being forced to work with … at genomes and seeing where the really hard things to sequence were, and wondering what those … what those were … for many millions, sometimes billions, of years. And understanding how those changes that evolution brokers are …

… Linking lignin engineering to drought stress resilience: RNA-seq and metabolomic insights in lignin biosynthetic pathway … Elucidating Sphagnum microbiome genetic interactions for improved growth at elevated … Adaptive strategies in a cosmopolitan and abundant soil …

… and you can still make more of it, then you start going into human trials or animal trials first, and going through … and the 90s. And so we started to be able to explore DNA sequencing and actually get to the DNA sequence – sequences … in terms of – well it’s really simple in terms of understanding it because it’s an assembly line. You just go …

… hands-on learning opportunities and ultimately, an understanding of the JGI’s role in enabling complex … at UC Berkeley is a program designed to foster a profound understanding of research methodologies within the realm of …

… I think for Natural Prodcast, I think the question that generally comes up that people come to me asking like is– … Science program. It used to actually stand for Community Sequencing Program. Also CSP, same acronym. But as JGI, as a … genomes. Fungal plant, algal genomes, a lot of effort goes into generating these data sets. There’s a lot of manual …

…   Our Sequencing Technologies Group is well-integrated across JGI departments to ensure a robust offering of sequencing capabilities and products to our users. This … and enabling state-of-the-art sample processing and sequencing capabilities. The Genomic Technologies Group, …