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… diversity of cell types and associated organisms, including fungal and bacterial symbionts, detrimental microbial … ‘omics methods. Here we were able to capture both plant and fungal expression patterns in root cross-sections. …

… what we know is they’re quite selective in some way for antifungal activity. They are also, some of them, are … being called an egg defense model. And so maybe there are compounds in there that we know there are compounds in there … And so then there isn’t horizontal transfer and so those pathways don’t have to be clustered so they end up probably …

… its effects on regulation of natural product biosynthetic pathways, which led her to a successfully funded JGI CSP … we can actually then put these in E. coli and add in our compounds of interest to start to understand whether this … students, we obviously can't put any antibiotics or antifungals in there. So they get just a smattering. JACKIE: …

… fungi remain largely mysterious. Only about 200,000 fungal species have been named. Among those sequenced, … Department of Energy (DOE) Joint Genome Institute (JGI)’s Fungal and Algal Science Program and JGI users have been at … studying species in isolation. The comparative power has uncovered remarkable evolutionary stories: how ancient yeast …

… episode is our conversation with Nancy Keller, a fantastic fungal natural products researcher from the University of … that you are the first person we’ve had on to talk about fungal natural products. I can say that I started in fungal … use that product and look in cell culture and see if this compound is having an impact. You know, maybe it is …

… DNA Synthesis and Single-Cell Genomics Vivian Ng Fungal Genomics …

… And I think also the quality that we provide. So for fungal and for a lot of our eukaryotic genomes, all our eukaryotic genomes. Fungal plant, algal genomes, a lot of effort goes into … and work within the DOE emission space of bioenergy, carbon cycling, biogeochemistry, bioproducts. So we cannot …

… Acids Res.  45(D1):D457-D465. Paez-Espino, D. et al. (2016) Uncovering Earth’s virome.  Nature   536:425-30 Kyrpides NC. … 24(6):425-7. Eloe-Fadrosh EA, et al. (2016) Metagenomics uncovers gaps in amplicon-based detection of microbial …

… what made you interested in plants and the natural compounds that they make? CASSANDRA QUAVE: Yeah, so I mean … could be used to treat these highly resistant bacterial and fungal pathogens. And we’ve actually just wrapped up a year, … technologies, NMR, mass spec, whatnot and then we’re comparing that to see what we’re able to pick out through …

… four forests, researchers have leveraged data from the 1000 Fungal Genomes project to form new connections between fungal guilds, genes and function. If a tree falls in the … soil. These fungi help shape a forest’s ecology. They store carbon and cycle key nutrients like nitrogen and …

… response to drought, from a large-scale field experiment to uncover the mechanisms behind sorghum’s capacity to produce … JGI in 2009 and it is considered to be a Flagship Plant. By uncovering and characterizing the mechanisms through which …