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… … Dan Udwary: Hey everybody! Welcome back for Natural Prodcast … discovery. It’s also the kind of book we can hand off to family members and friends as a way to introduce them to the … Usually when we do these interviews, most of the people that I think we’ve talked to so far I either know …

… … Dan Udwary: Hey, Alison Takemura: Hey, Dan. Dan Udwary: Today … goodness. I mean, if you were to find my scientific papers, that would be Katherine. Dan Udwary: Right. Kate Duncan: But … She talks to lots of great scientists outside of secondary metabolism, and if you like what we’re doing here, you’ll …

… … DAN: Welcome back for episode 9 of Natural Prodcast. This … SIMB, or the Society for Industrial Microbiology conference that took place in January this year in San Diego, and that … hypotheses, about the relationship between a compound or family of compounds and corresponding gene cluster or family …

… … DAN: You’re listening to the US Department of Energy Joint … a podcast about the science and scientists of secondary metabolism.  DAN: Hey there, and welcome to the first … Berkeley National Laboratory. Being a User Facility means that scientists from all over the world bring us big …

The JGI’s DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the … with U.S. and international scientists to drive innovations that align with DOE's missions. … The DNA Synthesis Program … vision for a sustainable, bio-based economy. … Genome to Enzymes and Pathways focuses on discovering and …

… such effort is targeted at environmental cells that are from candidate phyla, major branches in the phylogenetic tree … which highlights our skewed understanding of microbial metabolism towards a minority of cultivated bacteria, still …

… large with access to high-throughput sequencing, synthesis, and metabolomics at the JGI for projects of relevance to Department of Energy (DOE)  Mission Areas . Through this program, the DOE aims to advance … of our CSP: The Large Scale call is for expansive projects that leverage a range of JGI capabilities, and also requires …

… provide direct biochemical datasets to improve our understanding of microbial metabolism. Of particular interest is understanding the distributed and dynamic metabolite networks of environmental microbes and how they transform their environment. …

Below is a brief description of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it … of a successful sequencing project. It is imperative that users properly assess DNA or RNA mass prior to shipment …

… of secondary metabolites across bacteria, fungi, algae and plants. These molecules, which are not essential for … to facilitate the discovery of new bio-based molecules that can drive innovations in bioenergy, sustainable … products and the science and scientists of secondary metabolism. As the JGI acts on its goals in — and builds out …

… in biological systems, linking them with genomic data to enhance our understanding of genome science, organisms, and … metabolites, genes, and proteins. It also enables exploration of energy and nutrient exchange, as well as microbial and … enzymatic transformations, pathways, and how changes in metabolism can affect ecosystem functions. The Metabolomics …

Biology is currently experiencing a revolution brought on by rapid developments in genomics and other omics technologies.  The exponential growth of DNA … (2018) Programmed DNA destruction by miniature CRISPR-Cas14 enzymes. Science 362(6416):839-842. Duerkop BA, et al. …