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… first started out the natural product community was almost 100% bacterial. Only people working in mycotoxins worked … mostly coming out of China and India, very cheap for $100-$200. But you have so many contigs. This is a problem … Basidiomyetes might get to 50. Some of them go to over 100. There. That can be the problem. Whereas the bacteria, …

… tell a quick story. Looking back, the year was probably 2010, 2011, I was a, uh- actually, I’ve got the t-shirt on … is really happening, if people are really going to sequence 10 or 20 genomes at once then we really need to have … heard about biosynthetic gene clusters and it’s one of the 10 analysis that you do, then it’s very easy to think that, …

… people what that number is. BETSY PARKINSON: So micromolar, 10 to the negative 6th. Nanomolar, 10 to the negative 9th. Picomolar, 10 to the negative 12th. … nearby. And of those once we did the predictions, about 140 unique cyclic peptides. And from that, about 130 of them …

… proposals as well. I’ve been at the JGI for 20 years, and 10 of those years, I’ve been a project manager. MENAKA … amount that they can request. So the minimum request is 100 kb. The maximum request is 500 kb. DAN UDWARY: For DNA … chance of getting approved because you requested only 100 kb versus 500 kb. In the lab, they’re going to do the …

… pathogenesis . Science. 2006 Sep 1;313(5791):1261-6. doi: 10.1126/science.1128796 Science News of the Day: Stokstad E. Genetics. Genomes highlight …

… goal to have 1,000 women in the program over a span of 10 years. So typically about 80 to 100 women get selected each year as a cohort to experience … might have done the extraction at five days, seven days, 10 days. And suddenly, you’re then comparing a chemical …

… the number was. But I want to say it was like less than 10. Since, you know, a recent decade.  DAN: I’m sure that’s … to check her stat and she was absolutely correct. Since 2010 there have been eight new antibiotics added to the … C, and you’ve got a new molecule, right? And so if you have 1000 A’s and 1000 B’s and 1000 C’s, then if you’ve got a …

… And I set that up. And we finally got that to work 10 years later. But in the meantime there, we had people … a teaspoon of soil from outside, you maybe have to do a 10,000-fold dilution to plate that out. The deeper you go in the cave, the less dilution. You can be down to 1 on 100 in a deep portion of a cave. So it just– it really, …