Results

Multilab EcoFAB study shows highly reproducible physiology and depletion of soil metabolites by a model grass
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Proteogenomic analyses indicate bacterial methylotrophy and archaeal heterotrophy are prevalent below the grass root zone
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The Genetic Architecture of Shoot and Root Trait Divergence Between Mesic and Xeric Ecotypes of a Perennial Grass
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Yasuo Yoshikuni
… the power of DNA synthesis, strain engineering, and biosystems design for DOE-mission-relevant discovery and … , 2022 Ke et al., CRISPR-CRAGE enables rapid activation of secondary metabolite biosynthetic gene clusters in bacteria, Cell Chemical Biology , 2022 … R&D100 Award finalist 2019 …
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JGI@25: From Life at the Extremes to Editing Genomes
… accessible metagenomic datasets from a wide variety of ecosystems around the world, conducting iterative searches … Such proteins have been adapted for therapeutic application development by Mammoth Biosciences, one of several companies … scoutRNA Is Required for Some Type V CRISPR-Cas Systems Mol Cell. 2020 Aug 6;79(3):416-424.e5. doi: …
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A Functional Mini-Integrase in a Two-Protein Type V-C CRISPR System
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Evidence for the widespread distribution of CRISPR-Cas system in the Phylum Cyanobacteria
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Bacterial genome editing by coupling Cre-lox and CRISPR-Cas9 systems
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Convergent Bacterial Microbiotas in the Fungal Agricultural Systems of Insects
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Giant viruses with an expanded complement of translation system components
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Uncovering Novel Genomes from Earth’s Microbiomes
Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary metabolites for multiple applications.       … Berkeley National Laboratory (Berkeley Lab), and the  DOE Systems Biology Knowledgebase (KBase) . Metagenomics is the …
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Characterizing Communities: JGI Announces Latest CSP Portfolio
… integrated high-throughput sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  …
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