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Extracting the Secrets of Secondary Metabolites
Repeats) is the leading tool for accurately editing genomes, its effectiveness has historically been limited due … in 2019. Now, that power is poised to grow exponentially by combining it with CRISPR.  By employing CRAGE, … That work by JGI researchers was published April 2022 in Cell Chemical Biology . When it comes to insect killer P. …
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Model Fern Reveals Insight into DNA Thievery in Ferns
Open Green Genomes hits milestone with C. richardii The Science Fern genomes are huge, and incredibly complex — making it … next-generation plant biology. … The work conducted by the US Department of Energy Joint Genome Institute is …
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JGI Interns at UC Merced Earn CAMP Merit Awards
… at UC Merced. CAMP is a statewide initiative funded by the National Science Foundation (NSF) and supports …
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David Goodstein
… extensive structural mutation in the laboratory. The Plant Cell 35 (2), 644-672 A Sreedasyam et al., 2023. JGI Plant … of interest and gene copy number variation across multiple genomes.  eLife 11, e78526. Li et al., 2021.  Plant … et al., 2020.  Gradual polyploid genome evolution revealed by pan-genomic analysis of Brachypodium hybridum and its …
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JGI Scientists Pen Genome Watch Articles
… are sharing their expertise in environmental genomics by writing for the column Genome Watch in  Nature Reviews … for more sustainable agriculture and was written by JGI computational biologist Rekha Seshadri. Writing the  … move toward characterizing the human microbiome  by its genomes and metagenome , rather than just by 16S ribosomal …
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A Grass Model to Help Improve Giant Miscanthus
… into how the multiple chromosomes of  Miscanthus arose by ancient hybridization (polyploidy) and insights into the … Understanding the evolution of polyploidy, and how genomes respond to extra chromosome and gene copies, will … Miscanthus breeding programs. The team also sequenced genomes of numerous wild  Miscanthus lineages to better …
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New Research Finds Flagella in the Terrestrial Roots of Marine Bacteria
However, genome and metagenomic sequencing conducted by the U.S. Department of Energy Joint Genome Institute, a … for the bacteria to orient and swim than they would gain by pursuing nutrients and other resources in the open … Other surprises in the research include a similar loss of cell walls and a complex pattern of evolution for genes …
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Pinning Down a Piece of Photosynthesis
By studying the structure and function of a cyanobacterial … no one’s ever had a structure of before,” said Crysten Blaby-Haas, a research scientist at the JGI and Molecular … structure of the protein related to its function inside the cell, Grosjean used the JGI-developed  guideRNA and Sequence …
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Honey Bee Gut Microbiota Divvy Up Dinner
… absorbable solution of sugars. But pollen contains plant cell walls, which have complex, branching chains of polysaccharides called pectin and hemicellulose. While these two polysaccharides can yield sugar … that pollen’s pectin and hemicellulose are degraded mainly by just two clades:  Gilliamella,  which mostly resides in …
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A Redesign for Yeast’s Genome, Chromosome by Chromosome
To engineer yeast to do more, and understand genomes in general, Jef Boeke, Weimin Zhang (NYU Langone …
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JGI announces 2024 Functional Genomics awardees
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Microbial Genomics & Metagenomics (MGM) Workshop
… designed to familiarize users with the Integrated Microbial Genomes & Microbiomes (IMG/M) data and workflows for …
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