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… to expression, scientists can now opt for various shades of grey. The ability to fine-tune the level of gene expression allowed researchers to identify … can offer scientists a more colorful palette of options; beyond off and on, scientists can determine the level of …

… JGI-led team significantly expands the global diversity of large and giant viruses. While the microbes in a single … viruses in the same drop—the vast majority not harmful to humans could be even larger. Viruses infect bacteria, … likely to just scratch the surface of what’s out there.  Beyond these 2,000 MAGs extracted from 8,000 metagenomes, …

… the slightly murky waters in the tube look like a scoop of stormwater, complete with leaves, debris, and even … bacteria aren’t usually visible without the assistance of microscope. “It’s 5,000 times bigger than most bacteria. To put it into context, it would be like a human encountering another human as tall as Mount Everest,” …

… annotation in fungal genomes. The Science In a proof-of-concept study, researchers demonstrated that a new … the way for dissection of additional traits, in fungi and beyond. … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …

… to aid with genome assembly and transcriptome analysis of microbial, fungal, and plant research projects.  More … require input in the ~ 30 – 100ng range. Note that beyond quantity, input quality (i.e., presence of “intact” high-molecular weight DNA) is an important …

… New evidence shows anaerobic fungi can degrade the hardiest of plant components   The Science There are three main … the plant, like the brick-and-mortar of a building or the human skeleton. It’s more complex, and poisons enzymes and … accurate, and maybe anaerobic fungi living in soils or the guts of livestock were more capable than presumed. After …

… The JGI’s DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire chromosomes, advancing the development of biofuels, biochemicals and other bioenergy solutions.  … project. These advancements contribute to the development of new biofuels and sustainable biochemicals. The DNA …

… initiatives new to the JGI. Projects must be independent of ongoing JGI proposals, and lead PIs cannot have been lead … projects will provide pilot data to assess feasibility of a novel approach or form the foundation for a large-scale … may be submitted at any time as brief white papers. Letters of Intent are not required. Applicants may submit up to two …

… The Science Within the archaeal domain, there is a group of tiny hitchhikers. These organisms are abundant and yet … mini genomes to match. As a result, they cannot process all of the chemicals they need to survive. To fill in their … systems of these two organisms suggested new possibilities beyond the current understanding that CRISPR-Cas systems …

… for sustainable solutions to current problems facing humanity. A major focus are biofuel feedstock species and plant-microbe interactions, … a plant based bioeconomy where plants are a major source of chemical production and contribute to a healthier planet … The Plant Program advances our understanding of plants’ biological and ecological roles to foster …

… to link genomes with environments to understand how webs of microbes cycle carbon and sustain biomes via the development and application of advanced mass spectrometry approaches and model laboratory ecosystems (EcoFABs). … at the JGI. Click to learn more about the program's areas of focus, major initiatives and more.  …