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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
A group led by JGI scientists have made strides in improving and applying a … that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and his team  … more efficiently than one strain could on its own.  In work published in  Synthetic Biology , the team used CRAGE …
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Partners
The JGI leverages its existing partnerships and develops others providing complementary … RNA extractions to support plant and other efforts. The JGI works closely with DOE computational facilities (e.g., the …
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
JGI-led team significantly expands the global diversity of … archaea and eukaryotes, and they range in particle and genome size from small, to large and even giant. The genomes … together with their unicellular hosts,” Schulz added. The work also used resources of the  National Energy Research …
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The Power of One, Amplified
… a single low diversity hot spring sediment sample. Their work showed that single cell genomics can add significant … mobile genetic elements that were missed within paired metagenome assembled genomes (MAGs), and that dominant … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Emiley Eloe-Fadrosh
Dr. Eloe-Fadrosh joined the JGI in 2014 to pursue her research interests in microbial … training in human microbiome research at the Institute for Genome Sciences at the University of Maryland School of Medicine and her graduate work in microbial oceanography at Scripps Institution of …
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Cataloging the Microbes that Manage the Health of River Systems
Nature paper , researchers describe a dataset of microbial genomes sampled from rivers covering 90% of the watersheds … systems, these communities remain understudied. Through the JGI’s Community Science Program, Colorado State University … efforts, but also how data integration and sharing could work across platforms. … This work was partially supported …
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Better Genome Editing for Bioenergy
… problem: at a genetic level, how does  Y. lipolytica work? The project was a multi-institutional effort led by … included researchers at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User Facility. Y. lipolytica …
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Pinning Down a Piece of Photosynthesis
… and water into oxygen and sugars. How photosynthesis works, though, is much harder to pin down.  Photosynthesis … scientist at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Digging into Microbial Ecosystems Deep Underground
… “Microbes underpin so much of what we see on earth in terms of nutrient … deep underground, and before the pandemic, they took the JGI on a sampling field trip. One of the questions they’re … with first author Amundson in the journal Microbiome . The work builds off a proposal approved through a collaborative …
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New Vision, New Mission, New Plan: The JGI’s Next Five Years
New 5-year strategic plan outlines how the JGI will advance the bioeconomy, leveraging partnerships to … community. The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) has released its newest 5-Year … comprised of holding JGI-internal leadership and planning workshops, as well as collecting extensive input from all …
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David Goodstein
… equipment manufacturer KLA-Tencor before joining the JGI in 2002. Initially focused on building tools to … gene models in support of JGI’s contributions to the Human Genome Project, he began developing larger comparative … efforts expanded to include basal metazoans and plants. Working with a talented team of scientists and software …
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Doubling Down on Known Protein Families
… communities by looking at protein function within them. The work was led by a team of scientists at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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