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Ancient Algae Reveal Secrets of Plant Evolution
… and bioproducts — would further drive a strong bioeconomy. Summary Through the Community Science Program of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … Berkeley National Laboratory (Berkeley Lab), scientists sequenced the genomes of four  Zygnematophyceae algae, which …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… better understanding of nutrient cycling across the planet. Summary To understand more about how archaeal hosts and … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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When “The Blob” Made It Hotter Under the Water
… by extension, the ocean’s capacity to act as a carbon sink. Summary As global temperatures rise, so do instances of … samples. Genomic DNA extracted from the water samples were sequenced by the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Data Discovery Tool Helps Identify Microbial Roles within Metagenomes
… tool to correlate protein annotations with ratios of DNA sequence fragments from the ecosystems. Selecting a protein … problems, advancing their utility across the bioeconomy. Summary As described in a  recent  mSystems paper , a team at the DOE Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Innovative Technology Improves Our Understanding of Bacterial Cell Signaling
… cyclic di-GMP in bacteria through work enabled by the JGI’s Community Science Program (CSP) . The Impact Cyclic … real-time changes in cyclic di-GMP via live cell imaging. Summary From digestive tracts to plant surfaces and soil, … Ec YcgR, within the Nano-lantern scaffold. They then mined sequence databases for homologous YcgR proteins and chose a …
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Mining Metagenomes for Cas Proteins
… Cas14 proteins discovered from JGI’s IMG/M database and biochemically characterized at UC … Institute (JGI), a DOE Office of Science User Facility. The sequences were then biochemically characterized by a team … in sequencing and analyzing uncultivated microbes. Summary The CRISPR-Cas system is an immune mechanism in …
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Busting the Unbreakable Lignin
… landscape of biomass production and bioproduct engineering. Summary That organisms make use of cellulose and … Research Center. O’Malley is also affiliated with JBEI. The JGI data portals and pipelines helped identify potential … for lignin deconstruction. (The JGI also conducted RNA sequencing and alignment to the reference fungal  genome . …
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An Automated Tool for Assessing Virus Data Quality
… CheckV can help researchers assess virus sequence fragments and data quality. The Science Through … uncultivated viruses. Following up on those guidelines, JGI researchers have now developed CheckV (pronounced … and best practices for defining virus data quality. Summary Characterizing viral genome fragments can be …
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Natural Prodcast Episode 17: Cassandra Quave
… people aspects of things, because a lot of what we do at JGI in terms of the sequencing that we do is very people-disconnected, and … podcast hear me say this every third podcast or so. But JGI, our focus as a DOE, Department of Energy, user facility …
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Extracting the Secrets of Secondary Metabolites
… the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … can then employ CRISPR in a variety of microbial hosts. Summary Photorhabdus luminescens proves fatal to insects. It … CRISPR to knock out or activate genes, researchers at the JGI were able to monitor loss- and gain-of-function. The …
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iPHoP: A Matchmaker for Phages and their Hosts
… are microbes like bacteria, not humans. With metagenomic sequencing, researchers have found more of these viruses … kinds of ecosystems. However, matching these viral genetic sequences to their hosts is crucial to understanding what … interactions, nutrient cycling, or carbon sequestration. Summary Existing programs use a variety of approaches to …
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How Maize Makes An Antibiotic Cocktail
… as  Sorghum bicolor — a  candidate bioenergy feedstock and  JGI Flagship Plant — could produce at least 15 zealexins. … native substrates to produce additional novel antibiotics. Summary The zealexins are chemically complex, but their … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, through its  …
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