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The Megadata of Lake Mendota - Part 2: Souped Up Computing
This series is the story of a giant metagenome assembly from Wisconsin’s Lake Mendota. In this … we head there for a sense of what this supercomputing looks like. …
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Integrative visual omics of the white-rot fungus Polyporus brumalis exposes the biotechnological potential of its oxidative enzymes for delignifying raw plant biomass
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable … Director of Operations, shares her story of what it was like on the frontlines at the Joint Genome Institute. Hear … Center, JGI staff worked around the clock to generate the sequences of these three chromosomes. In 2004, they …
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A Complex Confection Decoded: Sugarcane Reference Genome
Sugarcane was the last major crop without a reference quality … Community Science Program; in 2018, a monoploid reference sequence of sugarcane was published as a step forward in … that durable resistance to brown rust disease caused by the fungus,  Puccinia melanocephala . This plant pathogen used …
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Metatranscriptomic Sequencing of Winter and Spring Planktonic Communities from Lake Erie, a Laurentian Great Lake
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Accelerating Metagenomics Discoveries with Deep Learning
On July 6, scientists from Lawrence Berkeley National Laboratory (Berkeley Lab) and … of proteins in order to conduct more efficient protein sequence alignments. He also aims to detect structural … Deep learning algorithms can vectorize faces… … so, why not proteins?         … The U.S. Department of Energy …
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Co‑cultivation of the anaerobic fungus Caecomyces churrovis with Methanobacterium bryantii enhances transcription of carbohydrate binding modules, dockerins, and pyruvate formate lyases on specific substrates
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Complete genome sequence of the halophilic bacterium Spirochaeta africana type strain (Z-7692T) from the alkaline Lake Magadi in the East African Rift
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Micro-Scale Applications Group
The Micro-Scale Applications group explores the genetic makeup of … access to cutting-edge cell sorting, DNA amplification, and sequence analysis to recover the genomes of uncultivated … now uses laser microdissection to selectively isolate and sequence microbial aggregates after first imaging with …
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Evolution of a Fungal Gene Expression Regulator
Describing the largest analysis to date of the modified DNA base 5mC … in fungi. The Science Changing an A, C, T or G in a genome sequence can lead to changes in protein structures and … (JGI), a DOE Office of Science User Facility, and others like it, are uncovering the true diversity of the fungal …
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JGI@25: Using Team Science to Build Communities Around Data
In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable … Spatafora of Oregon State University led the effort to sequence 1000 fungal genomes to create two reference genomes … or assembly right now, and eight more that we are likely to take forward with material in hand,” said Jeremy …
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Gene Expression: From On-Off Switch to Dial
Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science Scientists have developed a more … gene expression. They tested this new methodology in yeast ( Saccharomyces cerevisiae) to assess the potential of …
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