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… of Energy (DOE) Joint Genome Institute (JGI) is committed to advancing the field of genomics through open access to … the HGP, the JGI has sustained its commitment to uploading sequence data generated on behalf of its user community to … Nucleotide Sequence Database Collaboration (INSDC) has managed the growing corpus of sequence data for all …

… preview of how large-scale single cell genomics complements metagenomics studies. The Science Researchers demonstrated … to the other commonly used culture-independent sequencing approaches including amplicon and metagenomic sequencing. … snippets of microbial genomes directly from environmental sequence data, by piecing each genome together from large …

… pathogens, and associated viruses that all contribute to a dynamic ecosystem. We are interested in how plants … by microbial partners. We use a variety of genomics-powered tools to study this complexity, including single-cell and spatial … thaliana. Using a coupled experimental and computational approach, we employ various omics technologies, strain …

… that showcase our collaborations and capabilities to enable great science that will help solve energy and … of viruses impact many ecological processes, including carbon cycles. “Whether or not you planned it, viruses are … Along with highlighting the viruses in a given sample, metagenomics shed light on another key aspect of viruses in …

… how a fundamental mechanism of evolution allows microbes to adapt to changing environments. The Science The first … to adapt to changing environments. It also sheds light on why the rapid injection of mutations in a particular gene … prevent viruses from successfully replicating, even if they managed to enter the host cell. DGRs could prove to be …

… Proposals aim to sequence and annotate genomes from Antarctica to Africa … of efforts to develop pangenomes for these species, this approach would also allow researchers to learn more about … computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s Office of Science is …

… impact on the microbial communities within soil. Using metagenomics, scientists can shed light on hidden … AMGs in soil viruses thought to break down chitin, the gene sequences were cloned by the JGI.  The JGI’s DNA synthesis … and AMGs. It could spawn future research into understanding why these AMGs exist in the first place, and what function …

… organisms can do. And we need the field’s context to see why it matters.” As his career progressed, Hungate has … these amazing technologies that the JGI has to identify and sequence who’s making what, that the context at a microscale … Annual Meeting, Holmes discussed how to use genomics and metagenomics to better understand what is called the “virus …