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… possible by mining the datasets in the Integrated Microbial Genomes and Microbiomes (IMG/M) suite of tools managed by … led by Jennifer Doudna’s group at the University of California (UC), Berkeley, which is also affiliated with … potential waiting to be unearthed in sequencing and analyzing uncultivated microbes. Summary The CRISPR-Cas …

… For the last 15 years, Ray Turner has been one constant for … Berkeley Lab. For the last 15 years, Ray Turner has been one constant for the Joint Genome Institute. On July 1, … address some of the most pressing challenges of our time. For more information, please visit  …

… results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the microbiome of the earth, but most … a single cell and isolating it for analysis. Once it’s alone, the cell breaks apart and its DNA is copied millions of …

… tool that can help scientists engineer organisms for bioenergy applications. Cas9 needs guide RNA to lead it … in  Metabolic Engineering , a team of researchers likewise honed their tool before felling their research problem: at a … in the genome with CRISPR-Cas9 in order to interrogate each one’s function. However, the team first needed to fix a …

… fungal mitochondrial genome data, unlocking new potential for AI-driven studies of energy metabolism. The Science … nearly 10,000 new annotations of fungal mitochondrial genomes — the DNA found inside mitochondria, the … a widely used automated annotation tool missed at least one core gene in nearly half of those same genomes. The team …

… link viruses to their host(s), collaboration with JGI users for analyzing viral datasets, and the organization of community-building efforts in the field of viral ecogenomics. For this role, Dr. … Blaise Pascal, France M.S. in Data Analysis and Modeling for Life Sciences, Université Blaise Pascal, France Ph.D. in …

… an integrated approach to genome recovery from metagenomes. The Science Through the JGI’s Emerging Technologies … a team of researchers has been working on improving methods for isolating and characterizing entire microbial genomes … metagenomic data from Crystal Geyser in Utah (work also done by the Banfield lab in collaboration with the JGI), …

… technologies have led to an abundance of microbial genomes becoming available to the global research … the microbial diversity we know about, and proposes a path forward to curate and cultivate what is still unknown.  “We … it comes to isolate genome data, our real-world touchstones, we’re just scratching the proverbial Petri dish,” …