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Doubling Down on Known Protein Families
… big the room is.  A new study  published online Oct. 11, 2023 in  Nature highlights the vast array of functional … but we knew the families,” Kyrpides said. Yet, “almost 20 years of metagenomic data and metagenomic analysis, and … of new protein families had started to plateau in recent years, perhaps suggesting that scientists had “captured” …
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Getting to the Bottom of Fungal Functions Across Earth’s Forests
… this way was challenging, according to Martin. “Twelve years ago, when we mapped the first sequenced RNA from the … Fungal Genomes project changed that. This is a multi-year project in collaboration with the JGI to sequence 1000 … person at the Walnut Creek Marriott the week of September 30 – October 4, 2024.  … The U.S. Department of Energy Joint …
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The Power of One, Amplified
… in, on, and around the planet remain unknown. In recent years, advances in sequencing technologies and bioinformatic … diverse than those within more moderate ecosystems. A few years ago, a candidate bacterial lineage was identified from … Facility, is supported under Contract No. DE-AC02-05CH11231. This work was supported in part by a Natural Sciences …
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Enlarging Windows into Understanding Gene Functions
ENCODE project known as FUNCODE. “We noticed a few years ago that there is no shortage of fungal genomes … functional interpretation is as tough as it has been 10 years ago,” he said. “We thought about reconstructing gene …
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Help from Citrus’ Bitter, Hardier Cousin
JGI’s Daniel Rokhsar, published over the last half-dozen years, on the ancestral origins of  Citrus sinensis , the …
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Jane Grimwood Named HudsonAlpha Genomics Chair
… the simplest cotton genome ( Gossypium raimondii ) several years ago.   As well as the seminal Human Genome Project DOE …
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Waiting to Respire
… ancestral bacteria’s energy sources. More than two billion years ago, cyanobacteria acquired the ability to produce …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… rely on enzymes that have been evolving for billions of years. However, these enzymes are often loosely understood, … fungi and animal. This analysis led them to identify 2,938 putative AT  genes. Within the AT genes identified across … that even enzymes that evolved separately for billions of years have some common signatures of muli-substrate …
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The Expanding Universe of Methane Metabolisms in Archaea
… gas 20 times more potent than carbon dioxide. Billions of years ago, methane-producing archaea likely played a key … the oldest metabolisms, with the first traces possibly at ~3.5 Gy (billion years),” Borrel and Gribaldo said in an email. “Therefore, …
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A Community Resource for Secondary Metabolite Researchers
… public database for the research community. With more than 13 million BGCs in the catalog at the time of publication, it … is the largest repository of BGC sequence data from over 1.3 million publicly available bacterial and archaeal genome … expediting BGC and biosynthesis research.  Summary Over the years several secondary metabolites databases have been made …
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Tracing the Evolution of Shiitake Mushrooms
Researchers sequenced 11 samples from Asia–Australasia and 13 samples from the Americas to trace the evolution … Lentinula genus diverged roughly 28 million years ago, when the largest mammal ever, Paraceratherium, … samples was a global collaboration that brought together 39 researchers from eight different countries. Genome and …
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When “The Blob” Made It Hotter Under the Water
… as hurricanes and droughts. Another one began in late 2013, when a large patch of warm ocean water about a third the … United States began forming in Alaska. Over the next two years it slowly spread, raising water temperatures by a few … U.S. Department of Energy under Contract DE-AC02- 05CH11231, the G. Unger Vetlesen and Ambrose Monell Foundations, …
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