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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … mining, empowering research collaborators to take on ambitious synthetic biology experiments. A recent special issue of … Through a series of case studies, JGI scientific users share how they’ve worked with the JGI DNA Synthesis …
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Gut Fungi: Unexpected Source of Novel Chemicals
… off early from aerobic fungi, which can breathe oxygen — just like we do. Oxygen is a rich source of energy, and because anaerobic fungi can’t harness it, scientists long held … source of antibiotics. Indeed, these anaerobic fungi may be using these compounds for self-defense. But the compounds …
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Integrating Experimentation with Data
… $500     Students: $200      Postdocs: $250     Industry: $700    Thanks for joining the Joint Genome Institute … featured insightful presentations, dynamic panel discussions, informative poster sessions, thought-provoking … of Energy (DOE) Office of Science national scientific user facilities dedicated to advancing research in bioenergy …
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Calculating the Costs of Multiple Switchgrass Gene Copies
… team led by researchers at the University of Texas (UT) at Austin, the HudsonAlpha Institute for Biotechnology … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, has discovered that the candidate bioenergy … ecological and evolutionary consequences. A previous study conducted by our research team surveying the …
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High Five: Celebrating the JGI-UC Merced Genomics Internship Program
… tap into the diverse talent that UC Merced has is tremendous for us, and we are very grateful for this opportunity.” … reminded the audience of the internship’s import. “Let us not forget that UC Merced is still a young institution, …
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Bacteria and Fungi Divvy Up the Work in Forest Floor
… and what escapes to the atmosphere in the form of greenhouse gases (e.g., carbon dioxide, methane, and nitrous oxide). Summary To do this work, the international … a microbial community like that from a temperate coniferous forest floor — which Baldrian’s team was investigating. …
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Silver age of GOLD introduces new features
… (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … repositories, as well as project data entered by external users. The Impact One of the significant challenges in maximizing genomic data usage is having the appropriate contextual information, or …
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Finding the Fermenters
… of fermentative prokaryotes. The Science Most organisms use oxygen to convert food into energy. However, in … or no oxygen, life had found other ways to produce energy, using a process called fermentation. To better understand … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National …
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Honey Bee Gut Microbiota Divvy Up Dinner
… of the National Academy of Sciences . The team focused on the dominant bacterial clades shared between honey … pollen’s pectin and hemicellulose are degraded mainly by just two clades:  Gilliamella,  which mostly resides in the bee’s ileum, a structure analogous to the human small intestine; and  Bifidobacterium,  …
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Accelerating Metagenomics Discoveries with Deep Learning
… workshop, Volkan Sevim, a computational biologist at the US Department of Energy (DOE) Joint Genome Institute (JGI), … that low sequence identity may belie. The technology he’s using is magical; transform any length of amino acid sequence into a smaller, constant-length vector using deep learning. Vector representations allow homology …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… Studying the  genomes of microorganisms is incredibly useful for understanding the microbiome of the earth, but … To access the genomes of uncultured  microbes , scientists usually employ two different methods; shotgun metagenomic … and most genomes that were acquired through it were usually only around 30% complete.  Described in  ISME …
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Training the Next Generation of Talent
… Joint Genome Institute (DOE JGI), a DOE Office of Science user facility, Keedrian Olmstead was back on campus at the University of California, Merced to start … instructions for building and maintaining cells through the use of deep-sequencing technologies. The internship program …
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