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Streamlining Regulon Identification in Bacteria
… with their target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory … RNA sequencing of whole transcriptomes, and the third is determining the 5’-ends by 5’-end sequencing, from which those … had been experimentally verified in S. coelicolor . With results from the research, RIViT-seq data have increased the …
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Enlarging Windows into Understanding Gene Functions
… in sequences affect traits. In a text file, the rows of letters A, T, C and G appearing over and over in a … as FUNCODE. “We noticed a few years ago that there is no shortage of fungal genomes anymore, but their functional … in transcription factor binding, we build a lot on DAP results. We also employ RNA-Seq and diverse in silico …
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The Expanding Universe of Methane Metabolisms in Archaea
… methane-producing archaea likely played a key role in determining the composition of the Earth’s atmosphere and … new potential methanogenic, anaerobic methanotrophic and short-chain alkane-oxidizing archaea. They used IMG because … oxidation,” Borrel and Gribaldo said. “Overall, these results show a striking case of how metabolic diversity can …
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JGI-KBase Panel at SACNAS
Nov. 2: Getting Credit for Scientific Contributions of Any Size What is considered to be a scientific … students (and their mentors) how to begin establishing a professional presence through getting credit for any scientific contribution they make, whether as part of a course or internship, and before ever publishing a …
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Scaling Up Existing Skill Sets
Over the course of the summer, the JGI-UC Merced Genomics Internship paired … JGI internship has given me a great experience working intermediately between academia and industry, which is … JGI internship has given me a great experience working intermediately between academia and industry, which is …
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JGI Launches Latest Strategic Plan
For the Joint Genome Institute, the end of 2018 was marked by a celebration of contributing over one “petabase” – a quadrillion … and to help us calibrate progress toward our near- and long-term goals. And, by the way, as far as sequencing goes, the …
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2022 Progress Report
Pictured is a timelapse of the Integrative Genomics Building (IGB) seen above is … Area are also co-located in the IGB. Vision The vision of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office …
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User Support
The JGI Project Management Office carries out a number of activities to facilitate world-class science. DOE JGI … users to develop project requirements, define the scope of work and outline roles and responsibilities resulting in …
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Uncovering Novel Genomes from Earth’s Microbiomes
Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary … have uncovered genomes for just a small fraction of Earth’s microbial diversity. Because most microbes cannot … GEM (Genomes from Earth’s Microbiomes) catalog, this work results from a collaboration involving more than 200 …
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Rex Malmstrom
Dr. Malmstrom is a Staff Scientist and leader of the Microscale Applications group. Before joining the JGI in 2010, he made the first ever measurements of in situ growth rates and carbon consumption of SAR11 bacteria, the most abundant bacterial group in the …
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Training the Next Generation of Talent
Between DOE JGI, UC Merced Days after presenting the results of his summer research at the U.S. Department of Energy … run several programs for RNA-Seq assembly to determine which is best for the task at hand. “There are at …
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From Stress to Growth: The adaptive mechanisms of algae in changing Arctic waters
… sea ice in the Arctic has decreased by more than 30% in terms of quantity and thickness. Replacing older, thicker ice with … to biofuel. Summary Water temperatures and salinity determine how life thrives in the Arctic, and how different …
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