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… developed, tested and deployed a pipeline to first target cells from communities of uncultivated microbes, and then efficiently retrieve and characterize their genomes. The Impact Despite great strides in generating … world through bulk community sequencing (metagenomics) and single-cell genomics, the vast majority of microbes that …

In honor of the JGI's 25th anniversary in 2022, we have revisited a … energy and environmental challenges. In March 2008, the genome sequence of the forest fungus Laccaria bicolor was … of a mycorrhizal fungus shifted the focus from looking at single organisms to applying a broader ecosystem …

… biosphere), including the global carbon cycle. The JGI is sequencing large numbers of microbes and microbial … consequences of microbe-microbe interactions. Using metagenomes recovered directly from environmental samples and … growth because they had larger genome sizes and their cells were not observed to associate with host cells. In …

… was the last major crop without a reference quality genome and now crop researchers can work toward advancing … some duplicates, to sort through in order to form a single cohesive image. An approximately nine billion base … sugarcane was published as a step forward in this effort. Sequencing and assembling the genome required a custom …

Micro-Scale Applications head Rex Malmstrom and Metagenome Program head Emiley Eloe-Fadrosh outline more … metagenomics. One approach uses fluorescence-activated cell sorting (FACS) to sort cells into several small pools before sequencing to recover rare microbes. The technique was …