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A Redesign for Yeast’s Genome, Chromosome by Chromosome
… To engineer yeast to do more, and understand genomes in general, Jef Boeke, Weimin Zhang (NYU Langone Health) and Leslie Mitchell (Neochromosome) have worked … yeast’s native chromosomes with synthetic versions. This project has turned out to be an international collaboration, …
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Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
… polar oceans give rise to some of the largest food webs on Earth. And at their base are microscopic, photosynthetic … important cold-water communities of algae with warm-adapted ones, a trend that threatens to destabilize the delicate … UEA and including the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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Better Genome Editing for Bioenergy
… technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a powerful, high-throughput … at a genetic level, how does  Y. lipolytica work? The project was a multi-institutional effort led by … included researchers at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User …
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Dealing with Drought: Uncovering Sorghum’s Secrets
… Laboratory, and the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User … in Sorghum (EPICON) is a five-year, multi-institution project funded by the DOE Office of Biological and … under three watering conditions, and then collected root, leaf and rhizosphere (soil surrounding the root) samples …
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Metabolomics
… JGI by identifying the actual molecules present in an environment that influence system behavior.  Through this identification, metabolomics enables functional genome annotation, improves understanding of the role small … Find more details on the instrumentation we use and our methodology for …
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Igor Grigoriev
… at the JGI, a Senior Scientist at Lawrence Berkeley National Laboratory, and an Adjunct Professor of Plant and … of California, Berkeley. He contributed to the Human Genome Project and led annotation and analysis of diverse … Biology, Research Institute for Genetics and Selection of Industrial Organisms, Moscow, Russia Postdoctoral …
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JGI announces 2024 Functional Genomics awardees
… year, the JGI accepts proposals for state-of-the-art functional genomics research from reseachers who translate genomic … Through our CSP Functional Genomics call , we look for projects that will leverage the JGI’s DNA synthesis and omics capabilities to enhance understanding of gene and genome function. Tapping into these functions allows …
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Micro-Scale Applications Group
… The Micro-Scale Applications group explores the genetic makeup of natural microbial … technology in order to enhance the quality of single-cell genomes and directly link functional information with individual cells. Research Team    … internal analytical standards to accurately measure environmental microbiome activity levels.This functional assay …
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JGI announces 2025 Functional Genomics awardees
… Olufemi Isimikalu, Todd H. Oakley, BJ Philmus and Aaron M. Roshotte; [Below] Paul Scesa, Kathleen Scott, Tiffany … Through our  CSP Functional Genomics call , we look for projects that will leverage the JGI's DNA synthesis and omics capabilities to enhance understanding of gene and genome function. Tapping into these functions allows …
Learn more
A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
… Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary … collaborated with the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … of Bacteria and Archaea (GEBA) initiative. “This project has helped to define the current shape of the …
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A Grass Model to Help Improve Giant Miscanthus
… of polyploidy and perenniality. The Science A reference genome sequence and genomic toolkit for the perennial grass … Miscanthus sinensis has been published. Analysis of the genome sequence also provides insights into how the multiple … chromosomes of Miscanthus arose by ancient hybridization (polyploidy) and insights into the dynamics of gene …
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Jeremy Schmutz
… back to 1997, when he was working for the Stanford Human Genome Center, now the HudsonAlpha Institute for Biotechnology. There he constructed … 5, 16, and 19. Following the completion of the Human Genome Project in 2003, he developed sequencing, assembly, and …
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