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… Metabolism   Although there are still a large number of secondary metabolites yet to be discovered and their biosynthetic logics to be understood, accessing these untapped metabolic capabilities is often tedious … a given BGC in various hosts, availability of sequenced genomes, and computing resources needed to predict BGCs from …

… In April 2020, we mark both the 50th celebration of Earth Day on April 22, and DNA Day on April 25. As both … I’m Alison Takemura at the US Department of Energy Joint Genome Institute, or JGI.  Two special days occur in April: … short audio production, we’ll hear from Karolina Heyduk, an evolutionary plant biologist at the University of Hawai’i at …

… analyzing the enzymes present in the complex organic matrix of the forest floor, a team of researchers have found that … to identify proteins, the team compiled DNA sequences (metagenomes) and messenger RNA sequences (transcriptomes) from … suggest that fungi are breaking down plant fibers, like cellulose and lignin. Bacteria, on the other hand, appear to …

… The United States  is the world’s leading soybean producer , and soybeans are used to produce … causes Asian Soybean Rust (ASR) and is the major pathogen of soybean. Left uncontrolled, soybean rust could reduce … yields by as much as 90 percent. As part of the DOE Joint Genome Institute’s  2016 Community Science Program portfolio …

… Since joining the DOE Joint Genome Institute in 2016, Dr. Otani has … technologies and methodologies that facilitate discovery of new secondary metabolites. Prior to joining the JGI, he … BS, Engineering, Tokyo Institute of Technology Master's, Biotechnology, University of Tokyo …

… In this episode, undergraduates adopt genomes that the JGI … published in the literature. These students analyze the genomes, write reports, and publish first-author papers, … and Mark Soghomonian share what it was like to take on one of these genomes.  …

… Learn more about PhycoCosm, the largest interactive collection of sequenced algal genomes, omics data and comparative analysis tools developed …

… his summer research at the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science user … transcribed instructions for building and maintaining cells through the use of deep-sequencing technologies. The … I’ll take that knowledge back with me.” Now a second-year evolutionary biology student in David Ardell’s lab, he also …

… A new approach for improving functional annotation in fungal genomes. The Science In a proof-of-concept study, researchers demonstrated that a new … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science User Facility, is …

… guts and help them digest their last leafy meal. In their evolutionary history, these fungi branched off early from … called natural products . Yet, combing through the genomes of four anaerobic fungal species has revealed, for … recently, O’Malley’s team has begun to understand the outsized role the fungi play in digesting plant material in …

… A. Estrada-Graf, Nicole M. Fernandez; [Row 2]: Zachary Garvin, Chandan Kumar Gautam, Gareth Gillard, Audrey Goeckner, Jennifer Goff, Sarah Gonzalez Henao, Yang Hai, Julia G. Harenčár, … including metagenomics, metatranscriptomics and genome assembly to investigate microbial and plant …

… is not exclusively for Euryarchaeota. Atmospheric levels of methane, a potent greenhouse gas, regulate Earth’s … of archaea called  Euryarchaeota . These ancient, single-celled organisms thrive in most  environments devoid of … enabled by the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …