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Expanding Virophage Diversity
… Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant viruses. Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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DAP-seq Drives Robust Mapping of Gene Regulation
… assays yield an unprecedented view of plant evolution and adaptation.    Understanding how genes are regulated … to technical limitations and the sheer complexity of plant genomes. Now, with improvements to DNA Affinity Purification … robustness will enable researchers to propose multi-genome projects, opening new avenues for comparative regulatory …
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Genome sequences of key bacterial symbionts of entomopathogenic nematodes: Xenorhabdus cabanillasii DSM17905, Xenorhabdus ehlersii DSM16337, Xenorhabdus japonica DSM16522, Xenorhabdus koppenhoeferii DSM18168, and Xenorhabdus mauleonii DSM17908
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Promoting the Power of Viral Metagenomics
… early 2020, people all over the world have been forced to confront the awesome power that viruses have to affect nearly … is critical to understanding the role of viruses in many areas such as ecology, agriculture, and medicine. In the … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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JGI Early Career Researchers Featured in mSystems Special Issue
… issue of mSystems , out May 14, 2019, JGI researchers are among the authors who offer perspectives on what the next five … Micro-Scale Applications head Rex Malmstrom and Metagenome Program head Emiley Eloe-Fadrosh outline more … processes. A third approach steps away from reconstructing genomes directly from the environment and focuses on …
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JGI@25: Building a Better Bean
… In honor of the JGI's 25th anniversary in 2022, we have … of the University of Georgia sequenced and analyzed the genome of the common bean. That work was published online … The team sequenced and assembled a 473-million basepair genome of the common bean, identifying genes related to …
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JGI Workshop at SIMB NP Meeting
… Jan. 7: New Capabilities to Study Secondary Metabolism   Although there are still a large number … a given BGC in various hosts, availability of sequenced genomes, and computing resources needed to predict BGCs from available genome sequences. The DOE Joint Genome Institute (JGI), a …
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Katherine Louie
… became Platform Lead where she manages metabolomics production for community sequencing projects and heads R&D efforts to expand the metabolomics … rich metabolite profiles from diverse biological and environmental samples in support of user science.  Capabilities …
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Extracting the Secrets of Secondary Metabolites
… biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth … Repeats) is the leading tool for accurately editing genomes, its effectiveness has historically been limited due … CRAGE (Chassis-independent Recombinase-Assisted Genome Engineering) is a technique researchers can use to …
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A Step Toward Controlling Soybean Rust
… Rust (ASR) and is the major pathogen of soybean. Left uncontrolled, soybean rust could reduce crop yields by as much as 90 percent. As part of the DOE Joint Genome Institute’s  2016 Community Science Program portfolio … Research (INRA)  proposed sequencing a reference genome for  P. pachyrhizi to develop better strategies to …
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How Maize Makes An Antibiotic Cocktail
… a family of compounds that protects it against infections — using surprisingly few enzymes. The Science Maize ( … protect maize by fending off fungal and microbial infections. Scientists had assumed that maize synthesizes these … synthesized by the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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W. Berkeley Kauffman
… Berkeley is responsible for receiving and processing user samples. His R&D work focuses on the development of new applications utilizing a variety … of technologies to improve the JGI’s capabilities in the areas of metagenomics, single-particle genomics, and …
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