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… Cas9 needs guide RNA to lead it to the correct sequence to snip — but not all guides are effective. To ensure the gene editing tool will make the right cut, researchers created a set of guide RNAs that were effective … approach: CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the endonuclease where to cut, …

… provides new views of these relationships.  Recently , researchers used population genomics to find that while … to the global carbon cycle. Archaea are key players in this deep biosphere. They have adapted to acquire carbon … all operate in concert to form the foundation of this deep Earth ecosystem. For example, when certain viruses …

… Internship paired six UC Merced students with seven JGI researchers for bioinformatics internship opportunities in … which is something I didn’t even know existed before. Name: Deepika Gunasekaran Class Year: 2nd year graduate student in … to pursue a STEM career? I aspire to pursue a career in research and JGI has been the perfect experience in …

… Berkeley National Laboratory (Berkeley Lab) has now sequenced and assembled the genomes of these five cotton … insights on crop improvements at a genetic level, including why having multiple copies of their genomes (polyploidy) is … in this  Nature Genetics publication will facilitate deeper understanding of cotton biology and lead to higher …

… are symbionts and not free-living organisms. The Science Researchers employed multiple microbiology and ‘omics … in understanding the genomic basis and ecological consequences of microbe-microbe interactions. Using metagenomes … cells, the first member of the Archaea isolated from Deep Lake, the coldest place on Earth known to support life, …

… yet much of it remains unknown. For more than a decade, researchers around the world have collaborated with the U.S. … Group. Many of these bacterial and archaeal genome sequences have been generated using techniques that the JGI … Over the years more than 3,400 genomes have been sequenced from curated DSMZ isolates, for which quality DNA …