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… CRAGE-CRISPR combo helps further demystify biosynthetic gene clusters.  The … survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … CRAGE, researchers are no longer limited to using model host microbes; theoretically, any microbe can serve as the …

… Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science … to expression, scientists can now opt for various shades of grey. The ability to fine-tune the level of gene … area in the DNA, to determine which targets might benefit from an intermediate level of expression. Similar to the …

… The focus of this group, in recent years, has been to bring … The developed strains represent an additional phase of user-accessible project types, in which DNA-based … chromosomally integrated into a taxonomically diverse suite of microbial chassis strains for elevated opportunity for …

… Maize produces a family of compounds that protects it against infections — using … are important in plant growth, defense, and environmental interactions, and also have industrial applications, … the University of California, San Diego. The findings could help scientists produce more robust bioenergy plants in the …

… Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary … repository of 52,515 microbial draft genomes generated from environmental samples around the world, expanding the … including natural and agricultural soils, human- and animal-host associated, and ocean and other aquatic environments – …

… A fungus relies on bacteria to regulate key components of its reproductive machinery The Science To better … beneficial organisms (symbionts) are transmitted between host generations, researchers investigated the role that … fungal-bacterial relationships can shed light on how these interactions influence lipid production in Mucoromycotina …

… genome discoveries. Unlocking the intricate details of life’s genetic blueprint has long been a significant … efforts to build predictive models for the behaviors and interactions of complex systems.  One of its key innovations … AI models. I hope that the JGI will eventually not only host data, but also host these models — while helping its …