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… called terpenes. Terpenes are made via a tangled network of enzymes in plants. To better pinpoint the biosynthetic … projects in our group. It’s enabled us to accelerate gene, enzymes, and pathway discovery approaches and provided the … and then basically exploded, so that the molecules and enzymes that were once trapped inside are now, still …

… of 13 JGI scientists since the program’s inception. In 2014, JGI’s Zhong Wang and Science Programs Deputy Axel Visel … and hard work have carried it through the difficult early stages, so I can begin biological analysis of the data sooner … and Blood Institute in August 2018 Travis Lawrence (2014 graduate intern): Accepted a post-doctoral position with …

… processing these sturdy materials, rumen microbes and their enzymes are an optimal study subject that could lead to more … paper in the journal Science. It detailed how they’d used metagenomics — a then-novel approach which allows scientists … involved in the digestion process.  “We wanted to find the enzymes that make the rumen such an efficient …

… monomers, it’s only with the aid of specialized bacterial enzymes. Honey bees rely on their gut microbiota to produce these enzymes to break down polysaccharides. But scientists have … including collecting and analyzing the honey bee gut metagenome, which was done with the help of the US Department …

… little exception, organisms have figured out how to create enzymes that break these components down into glucose. It’s … or the human skeleton. It’s more complex, and poisons enzymes and the  microbes that make them. It’s known that … Research of the U.S. Department of Energy grant DE-SC0020420 (MAO), Institute for Collaborative Biotechnologies …

… of which contain a wide array of plant cell-wall degrading enzymes (PCWDEs) that allow them to efficiently break down … also being used in the biotechnology industry to produce enzymes, proteins, and other chemicals. Summary Filamentous … this information triggers pathways to determine which enzymes should be deployed in what order to most efficiently …

CRISPR-Cas9 work, the Doudna lab at UC Berkeley seeks other enzymes in the CRISPR-Cas system. For the past few years … system’s immense collection of publicly accessible metagenomic datasets from a wide variety of ecosystems around … Some Type V CRISPR-Cas Systems Mol Cell. 2020 Aug 6;79(3):416-424.e5. doi: 10.1016/j.molcel.2020.06.022. Wright AV et …

… put together what they called the Hungate1000, a catalog of 410 rumen microbe genomes. The project relied upon resources … microbes gave researchers access to a collection of novel enzymes — many of which contained interesting properties in … originally sequenced in the Hungate1000 collection harbor enzymes that could be useful for transcriptomic engineering. …

… mutation in the laboratory. The Plant Cell 35 (2), 644-672 A Sreedasyam et al., 2023. JGI Plant Gene Atlas: an … the plant kingdom. Nucleic acids research 51 (16), 8383-8401. JT Lovell et al., 2022. GENESPACE tracks regions of …

… scientists usually employ two different methods; shotgun metagenomic sequencing and single-cell sequencing. For years, … genomes from microorganisms are shotgun (group) metagenomic sequencing and single-cell (individual) … of Energy Joint Genome Institute (https:// ror.org/04xm1d337), a DOE Office of Science User Facility, is …