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… of guide RNAs that were effective against 94 percent of the genes in a lipid-prolific yeast. The Impact The team used … of guide RNAs on  Yarrowia lipolytica to identify essential genes and genes that lead to increased lipid production. … cut, but these “single guide” RNAs (sgRNAs) can be faulty. Without a good sgRNA, Cas9 is ineffective and leaves the …

… and more complex patterns of inheritance. The additional genes provided by these chromosomes can contribute to novel … during the winter and grows anew the following spring without requiring replanting. Miscanthus is especially … nutrients from one growing season to the next. By studying genes that are turned “on” or “off” at different times and …

… functional assay lets us move beyond cataloging the genes of microorganisms and start making quantitative …

… viruses. Almost all known virophage genomes share only four genes in common: major and minor capsid proteins (MCP and … diverse new virophage genomes containing all four core genes. These virophages were found in diverse habitats … classified into 27 distinct clades (17 of them without previously known representatives). Of these, 89 …

… Investigator Program, through The Paul G. Allen Frontiers Group, the National Science Foundation …