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Trent Northen
… to link genomes with environments to understand how webs of microbes cycle carbon and sustain biomes via the development and application of advanced mass spectrometry approaches and model laboratory ecosystems (EcoFABs). … at the JGI. Click to learn more about the program's areas of focus, major initiatives and more.  …
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From Competition to Cooperation
… Tracking evolution of symbiotic lifestyles across multiple fungal lineages. The … role in soil carbon storage. Summary There are three types of fungal saprotrophs in the forest. White rot can break … will assist researchers in moving toward functional genomics studies to learn more about the inner workings of …
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Pinning Down a Piece of Photosynthesis
… By studying the structure and function of a cyanobacterial protein, researchers have new insights … cycle carbon in changing conditions. The products of photosynthesis are easy to point out. Plants, algae and … what is now the  Community Science Program Functional Genomics proposal call, the JGI synthesized hundreds of  …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… a new methodology, scientists are now getting more complete genomic results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the … usually employ two different methods; shotgun metagenomic sequencing and single-cell sequencing. For years, …
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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
… communities than ever before — especially with the prospect of meta-analyses boosted by AI and Machine Learning — JGI … said. Informed by other community-driven standards from the Genomic Standards Consortium, Wilhelm and Simpson assembled … with a concrete experimental plan for a ring test, or a survey. Together, they will set up a broad experiment to …
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JGI Mural
… The JGI mural on the 3rd floor of the Integrative Genomics Building whimsically references … to advancing the frontiers of environmental and energy genomics. Click on the images below to learn about the …
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RECAP: Keynote Speakers Talk Innovation at 2022 JGI Annual Meeting
… The JGI was honored to host some of the brightest minds in genetics as part of our  2022 … hybrid event, with guests joining onsite at the Integrative Genomics Building at Lawrence Berkeley National Laboratory … (already known as CRISPR) that came up in her team’s metagenomic  samples . While Banfield continued exploring the …
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Mining Public Databases Yields Largest Map of Fungal Mitochondrial Genomes to Date
… genome data, unlocking new potential for AI-driven studies of energy metabolism. The Science Researchers produced … search environmental data, they developed a two-stage metagenomic detection pipeline: First, they scanned over 26,000 … ribosomal RNA sequences. The next step applied metagenomic binning (grouping sequencing reads by their likely …
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High Five: Celebrating the JGI-UC Merced Genomics Internship Program
… than 20 UC Merced students have contributed to the research of 13 JGI scientists since the program’s inception. In 2014, … around the world. That said, we recognize that workforce in genomics, including JGI, is not representative of the … graduate student summer research experience at the JGI, the Genomics Internship Program expanded to include UC Merced …
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Doubling Down on Known Protein Families
… online Oct. 11, 2023 in  Nature highlights the vast array of functional diversity of microbes through a novel approach … replicating a whole community is impossible.  Metagenomic sequencing allows researchers to study the entire … the families,” Kyrpides said. Yet, “almost 20 years of metagenomic data and metagenomic analysis, and still there has …
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Better Genome Editing for Bioenergy
… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in … tool will make the right cut, researchers created a set of guide RNAs that were effective against 94 percent of the genes in a lipid-prolific yeast. The Impact The team … MB) and NSF  1706545 (IW). HA and JW were supported by the Office of Naval Research under grant  N00014-15-1-2785 . JW …
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JGI@25: Strengthening Soybean
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … U.S. Not only does it pair with maize, the dominant source of bioethanol, in crop rotation, but soybean ( Glycine max ) …
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