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… regulate Earth’s climate. Most methane is produced in environments without oxygen through a process called … therefore play a critical role in the global carbon cycle, and are of significant interest for their potential contributions to a sustainable bioeconomy, including, …

… biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth … Interspaced Short Palindromic Repeats) is the leading tool for accurately editing genomes, its effectiveness has historically been limited due to the lack of robust tools available for carrying CRISPR into microorganisms. …

… single-cell genomic approach to bioprospecting. The Science One of the most vital pieces of equipment for fly fishing is … of Science User Facility located at Lawrence Berkeley National Laboratory (Berkeley Lab). Using a single-cell screen, … cellulose-degrading microbes. The new technique is another tool for microbial ecologists to learn more about the …

… array of microorganisms adapted to living in extreme conditions. At these vents, and underwater volcanoes,  researchers … studied microbial communities across five oceanic regions. In doing so, they found a high degree of variability in … This work was funded by the US-National Science Foundation grants OCE-0728391, OCE-0937404, …

… Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary … type-strain deposits. All of these genome sequences and the tools to compare them are available on the JGI’s Integrated … follow up work, but also maintains various bioinformatic tools and comprehensive curated databases, including …

… By leveraging new tools and large-scale data mining, JGI researchers nearly tripled the available fungal mitochondrial genome data, unlocking new potential for AI-driven … diversity in complex biological systems. By making the tools and data available through MycoCosm — a platform …

… hitchhikers. These organisms are abundant and yet exceptionally small, with mini genomes to match. As a result, they … to survive. To fill in their nutrient gaps, they must latch onto a larger host — often, a fellow archaeal microbe. … One of these systems, the CRISPR-Cas9 system, is a powerful tool in gene editing, but many other systems exist. …

… (UEC) represents the JGI user community and is responsible for providing input and advice on JGI policies and practices that affect users and their … as well as proposal review procedures and the organization of the JGI Annual Meeting. Any investigator who has been …

… Congratulations to the 2020 Highly Cited Researchers at the … are part of a team that  developed CheckV , an automated tool to help researchers assess and improve the quality of … team that  released a reference genome sequence and genomic toolkit for the perennial grass  Miscanthus sinensis in  …

… The JGI’s Genomes OnLine Database celebrates 25 years as a vital resource for data contextualization The Science Since its launch 25 years ago, the  Genomes … U.S. Department of Energy operated [DE-AC02-05CH11231]; National Energy Research Scientific Computing Center, which is …